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fdx2 ferredoxin 2 [ Danio rerio (zebrafish) ]

Gene ID: 767726, updated on 12-Sep-2024

Summary

Official Symbol
fdx2provided by ZNC
Official Full Name
ferredoxin 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-1046
See related
Ensembl:ENSDARG00000052190 AllianceGenome:ZFIN:ZDB-GENE-060929-1046
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fdx1l; zgc:153554
Summary
Predicted to enable 2 iron, 2 sulfur cluster binding activity; electron transfer activity; and metal ion binding activity. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See fdx2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (149405..152955)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (131354..134904)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene kelch-like ECH-associated protein 1b Neighboring gene sphingosine-1-phosphate receptor 5b Neighboring gene zinc finger GATA like protein 1 Neighboring gene uncharacterized LOC137495904 Neighboring gene LYL1 basic helix-loop-helix family member

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC153554

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables electron transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables electron transfer activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within P450-containing electron transport chain IEA
Inferred from Electronic Annotation
more info
 
involved_in [2Fe-2S] cluster assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of [4Fe-4S] cluster assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in electron transport chain IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ferredoxin-2, mitochondrial
Names
adrenodoxin-like protein, mitochondrial
ferredoxin 1-like
ferredoxin-1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076664.2NP_001070132.1  ferredoxin-2, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001070132.1

    Status: VALIDATED

    Source sequence(s)
    CABZ01066699, EH493611, EH559468, EH612574
    UniProtKB/Swiss-Prot
    Q08C57
    Related
    ENSDARP00000131094.2, ENSDART00000161154.2
    Conserved Domains (1) summary
    PLN02593
    Location:80195
    PLN02593; adrenodoxin-like ferredoxin protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    149405..152955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)