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sh3glb1a SH3-domain GRB2-like endophilin B1a [ Danio rerio (zebrafish) ]

Gene ID: 792229, updated on 12-Sep-2024

Summary

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Official Symbol
sh3glb1aprovided by ZNC
Official Full Name
SH3-domain GRB2-like endophilin B1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-89
See related
Ensembl:ENSDARG00000045294 AllianceGenome:ZFIN:ZDB-GENE-050417-89
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc55h11; fj98d09; sh3glb1; wu:fc55h11; wu:fj98d09; zgc:110259
Summary
Predicted to be involved in membrane organization. Predicted to act upstream of or within apoptotic process. Predicted to be located in Golgi membrane and mitochondrial outer membrane. Predicted to be active in membrane. Orthologous to human SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See sh3glb1a in Genome Data Viewer
Location:
chromosome: 24
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (28383322..28398100)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (28303840..28318941)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438353 Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit a Neighboring gene negative regulator of reactive oxygen species Neighboring gene F-box protein 45

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC110259

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
endophilin-B1a
Names
SH3-domain GRB2-like endophilin B1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017617.1 → NP_001017617.1  endophilin-B1a

    See identical proteins and their annotated locations for NP_001017617.1

    Status: PROVISIONAL

    Source sequence(s)
    BC092831
    UniProtKB/TrEMBL
    Q568J6
    Related
    ENSDARP00000018632.6, ENSDART00000018095.8
    Conserved Domains (2) summary
    cd11945
    Location:300 → 360
    SH3_Endophilin_B1; Src homology 3 domain of Endophilin-B1
    cl12013
    Location:21 → 249
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    28383322..28398100
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009297515.4 → XP_009295790.1  endophilin-B1a isoform X1

    UniProtKB/TrEMBL
    A0A8M3AW37
    Conserved Domains (2) summary
    cd11945
    Location:338 → 398
    SH3_Endophilin_B1; Src homology 3 domain of Endophilin-B1
    cl12013
    Location:21 → 287
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395180.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    52119..66942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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