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galk2 galactokinase 2 [ Danio rerio (zebrafish) ]

Gene ID: 792268, updated on 18-Sep-2024

Summary

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Official Symbol
galk2provided by ZNC
Official Full Name
galactokinase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-143
See related
Ensembl:ENSDARG00000004059 AllianceGenome:ZFIN:ZDB-GENE-041114-143
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb43h07; wu:fb43h07; zgc:101686
Summary
Predicted to enable galactokinase activity. Predicted to be involved in galactose metabolic process. Predicted to act upstream of or within carbohydrate phosphorylation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human GALK2 (galactokinase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See galk2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (32390817..32400209)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (31979860..31989252)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103909877 Neighboring gene uncharacterized LOC101882990 Neighboring gene ATPase phospholipid transporting 8B4 Neighboring gene sulfide quinone oxidoreductase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3. de la Garza G, et al. J Invest Dermatol, 2013 Jan. PMID 22931925, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC101686, MGC192908

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables N-acetylgalactosamine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables galactokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables galactokinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in galactose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within galactose metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
N-acetylgalactosamine kinase
NP_001007433.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007432.2 → NP_001007433.2  N-acetylgalactosamine kinase

    Status: VALIDATED

    Source sequence(s)
    BX005048, CU372926
    UniProtKB/TrEMBL
    A0A8M1N3C3, E7FDP4
    Related
    ENSDARP00000005687.9, ENSDART00000012600.11
    Conserved Domains (3) summary
    PLN02521
    Location:16 → 453
    PLN02521; galactokinase
    pfam08544
    Location:356 → 428
    GHMP_kinases_C; GHMP kinases C terminal
    pfam10509
    Location:23 → 71
    GalKase_gal_bdg; Galactokinase galactose-binding signature

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    32390817..32400209
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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