U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tgm1l3 transglutaminase 1 like 3 [ Danio rerio (zebrafish) ]

Gene ID: 793448, updated on 28-Oct-2024

Summary

Official Symbol
tgm1l3provided by ZNC
Official Full Name
transglutaminase 1 like 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-120718-1
See related
AllianceGenome:ZFIN:ZDB-GENE-120718-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable metal ion binding activity and protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within keratinization and peptide cross-linking. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1. Orthologous to human TGM1 (transglutaminase 1). [provided by Alliance of Genome Resources, Oct 2024]
Annotation information
Annotation category: partial on reference assembly
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See tgm1l3 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (40234646..40276231, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (40277504..40297530)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene transglutaminase 1 like 2 Neighboring gene transglutaminase 1-like 6 Neighboring gene terminal nucleotidyltransferase 5Ab Neighboring gene ELOVL fatty acid elongase 4b Neighboring gene uncharacterized LOC137489148 Neighboring gene MTCL family member 3b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein-glutamine gamma-glutamyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within keratinization IEA
Inferred from Electronic Annotation
more info
 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within peptide cross-linking IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein-glutamine gamma-glutamyltransferase K
Names
TG1-48

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    40234646..40276231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001331878.8XP_001331914.1  protein-glutamine gamma-glutamyltransferase K

    UniProtKB/TrEMBL
    A0A8M1Q6T7
    Conserved Domains (5) summary
    smart00460
    Location:429520
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:428565
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00868
    Location:166283
    Transglut_N; Transglutaminase family
    pfam00927
    Location:761846
    Transglut_C; Transglutaminase family, C-terminal ig like domain
    pfam02389
    Location:42128
    Cornifin; Cornifin (SPRR) family