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serbp1b SERPINE1 mRNA binding protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 797732, updated on 2-Nov-2024

Summary

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Official Symbol
serbp1bprovided by ZNC
Official Full Name
SERPINE1 mRNA binding protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031118-196
See related
Ensembl:ENSDARG00000087421 AllianceGenome:ZFIN:ZDB-GENE-031118-196
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc66f06; wu:fc66f06
Summary
Predicted to enable mRNA 3'-UTR binding activity. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERBP1 (SERPINE1 mRNA binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See serbp1b in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2628405..2642077, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (2786506..2800211, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene myosin, light chain 13 Neighboring gene translation initiation factor eIF2B subunit epsilon-like Neighboring gene mitochondrial E3 ubiquitin protein ligase 3 Neighboring gene aquaporin 1a (Colton blood group), tandem duplicate 1 Neighboring gene aquaporin 1a (Colton blood group), tandem duplicate 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SERPINE1 mRNA-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    2628405..2642077 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001338162.9 → XP_001338198.4  SERPINE1 mRNA-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M1Q7B8
    Conserved Domains (2) summary
    pfam04774
    Location:181 → 283
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
    pfam16174
    Location:5 → 97
    IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal

  2. XM_005171128.4 → XP_005171185.1  SERPINE1 mRNA-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BIU7, E7EYQ0
    Related
    ENSDARP00000109449.3, ENSDART00000124032.4
    Conserved Domains (2) summary
    pfam04774
    Location:181 → 283
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
    pfam16174
    Location:5 → 97
    IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal
Nucleotide Protein Strain
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