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PAP1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 814646, updated on 22-Aug-2024

Summary

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Official Symbol
PAP1
Primary source
Araport:AT2G01180
Locus tag
AT2G01180
See related
TAIR:AT2G01180
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATLPP1; ATPAP1; F10A8.6; F10A8_6; LIPID PHOSPHATE PHOSPHATASE 1; LPP1; phosphatidic acid phosphatase 1
Summary
Encodes phosphatidate phosphatase. Up-regulated by genotoxic stress (gamma ray or UV-B) and elicitor treatments with mastoparan and harpin. Expressed in roots and leaves.
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Genomic context

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See PAP1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (106621..108829, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene bidirectional amino acid transporter 1 Neighboring gene uncharacterized protein Neighboring gene Octicosapeptide/Phox/Bem1p family protein Neighboring gene indole-3-acetic acid inducible 32 Neighboring gene Leucine-rich repeat protein kinase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lipid phosphate phosphatases in Arabidopsis. Regulation of the AtLPP1 gene in response to stress. Pierrugues O, et al. J Biol Chem, 2001 Jun 8. PMID 11278556
  2. The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition. Caillaud MC, et al. PLoS Pathog, 2014 Oct. PMID 25393742, Free PMC Article
  3. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
  4. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
  5. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genome-Wide Identification of PAP1 Direct Targets in Regulating Seed Anthocyanin Biosynthesis in Arabidopsis.
    Title: Genome-Wide Identification of PAP1 Direct Targets in Regulating Seed Anthocyanin Biosynthesis in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001335038.1
NM_001335041.1
NM_001335042.1
NM_001335043.1
NM_126179.5
NM_201660.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phospholipid metabolic process NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within response to UV-B IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
phosphatidic acid phosphatase 1
NP_001318171.1
  • phosphatidic acid phosphatase 1 (PAP1); FUNCTIONS IN: phosphatidate phosphatase activity; INVOLVED IN: phospholipid metabolic process, response to stress; LOCATED IN: plasma membrane, integral to plasma membrane; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (InterPro:IPR016118), Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); BEST Arabidopsis thaliana protein match is: lipid phosphate phosphatase 3 (TAIR:AT3G02600.1); Has 2118 Blast hits to 2110 proteins in 392 species: Archae - 9; Bacteria - 357; Metazoa - 920; Fungi - 399; Plants - 198; Viruses - 3; Other Eukaryotes - 232 (source: NCBI BLink).
NP_973389.1
  • phosphatidic acid phosphatase 1 (PAP1); FUNCTIONS IN: phosphatidate phosphatase activity; INVOLVED IN: phospholipid metabolic process, response to stress; LOCATED IN: plasma membrane, integral to plasma membrane; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (InterPro:IPR016118), Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); BEST Arabidopsis thaliana protein match is: lipid phosphate phosphatase 3 (TAIR:AT3G02600.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    106621..108829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001335040.1 → NP_001323950.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3EC91, Q8H0G3, Q8LDP8, Q945N3, Q94LY6, Q9ZU49
    UniProtKB/TrEMBL
    A0A5S9WW89, A0A654EQX5
    Conserved Domains (1) summary
    PLN02715
    Location:1 → 327
    PLN02715; lipid phosphate phosphatase

  2. NM_001335039.1 → NP_001323948.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AYQ5

  3. NM_001335038.1 → NP_001318171.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3EC91, Q8H0G3, Q8LDP8, Q945N3, Q94LY6, Q9ZU49
    UniProtKB/TrEMBL
    A0A5S9WW89, A0A654EQX5
    Conserved Domains (1) summary
    PLN02715
    Location:1 → 327
    PLN02715; lipid phosphate phosphatase

  4. NM_001335041.1 → NP_001323949.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VSS9
    Conserved Domains (1) summary
    PLN02715
    Location:1 → 302
    PLN02715; lipid phosphate phosphatase

  5. NM_001335042.1 → NP_001323952.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AYJ4

  6. NM_001335043.1 → NP_001323951.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AYQ5

  7. NM_126179.5 → NP_565255.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565255.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3EC91, Q8H0G3, Q8LDP8, Q945N3, Q94LY6, Q9ZU49
    UniProtKB/TrEMBL
    A0A5S9WW89, A0A654EQX5
    Conserved Domains (1) summary
    PLN02715
    Location:1 → 327
    PLN02715; lipid phosphate phosphatase

  8. NM_201660.2 → NP_973389.1  phosphatidic acid phosphatase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973389.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VSS9
    Conserved Domains (1) summary
    PLN02715
    Location:1 → 302
    PLN02715; lipid phosphate phosphatase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZU49.2

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