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MRP2 mitochondrial 37S ribosomal protein MRP2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856295, updated on 18-Sep-2024

Summary

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Official Symbol
MRP2
Official Full Name
mitochondrial 37S ribosomal protein MRP2
Primary source
SGD:S000006370
Locus tag
YPR166C
See related
AllianceGenome:SGD:S000006370; FungiDB:YPR166C; VEuPathDB:YPR166C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
uS14m
Summary
A structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 38. Orthologous to human MRPS14 (mitochondrial ribosomal protein S14). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MRP2 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (876282..876629, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mms1p Neighboring gene Rho family GTPase RHO1 Neighboring gene phosphoadenylyl-sulfate reductase (thioredoxin) Neighboring gene mediator complex subunit NUT2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Assembly of the mitochondrial membrane system. MRP1 and MRP2, two yeast nuclear genes coding for mitochondrial ribosomal proteins. Myers AM, et al. J Biol Chem, 1987 Mar 5. PMID 3029111
  2. Incorporation of the yeast mitochondrial ribosomal protein Mrp2 into ribosomal subunits requires the mitochondrially encoded Var1 protein. Davis SC, et al. Mol Gen Genet, 1995 May 10. PMID 7770043
  3. Surveillance of 3' mRNA cleavage during transcription termination requires CF IB/Hrp1. Li J, et al. Nucleic Acids Res, 2023 Sep 8. PMID 37351636, Free PMC Article
  4. Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues. Saveanu C, et al. J Biol Chem, 2001 May 11. PMID 11278769
  5. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 37S ribosomal protein MRP2
NP_015492.1
  • Mitochondrial ribosomal protein of the small subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    876282..876629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184263.1 → NP_015492.1  TPA: mitochondrial 37S ribosomal protein MRP2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015492.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4G7, P10663
    UniProtKB/TrEMBL
    A6ZX42, B3LKC7, C7GP49, C8ZJJ2, G2WPX9, N1NWJ9
    Conserved Domains (1) summary
    pfam00253
    Location:61 → 112
    Ribosomal_S14; Ribosomal protein S14p/S29e
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P10663.1

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