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    Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein [ Mus musculus (house mouse) ]

    Gene ID: 19039, updated on 28-Oct-2024

    Summary

    Official Symbol
    Lgals3bpprovided by MGI
    Official Full Name
    lectin, galactoside-binding, soluble, 3 binding proteinprovided by MGI
    Primary source
    MGI:MGI:99554
    See related
    Ensembl:ENSMUSG00000033880 AllianceGenome:MGI:99554
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    90K; CyCAP; Ppicap; MAC-2BP; Tango10b
    Summary
    Predicted to enable scavenger receptor activity. Predicted to be involved in cell adhesion and vesicle-mediated transport. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and liver and biliary system. Orthologous to human LGALS3BP (galectin 3 binding protein). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in mammary gland adult (RPKM 204.1), duodenum adult (RPKM 185.6) and 19 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Lgals3bp in Genome Data Viewer
    Location:
    11 E2; 11 83.14 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (118283573..118292787, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (118392747..118401959, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 36 Neighboring gene STARR-positive B cell enhancer ABC_E1852 Neighboring gene STARR-seq mESC enhancer starr_31299 Neighboring gene tissue inhibitor of metalloproteinase 2 Neighboring gene CEP295 N-terminal like Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:118209837-118210038 Neighboring gene STARR-seq mESC enhancer starr_31301 Neighboring gene STARR-positive B cell enhancer ABC_E5311 Neighboring gene calcium activated nucleotidase 1 Neighboring gene predicted gene, 35598

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (8) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables scavenger receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables scavenger receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    galectin-3-binding protein
    Names
    cyp-C-associated protein
    mama
    peptidylprolyl isomerase C-associated protein
    NP_035280.1
    XP_036012322.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011150.3NP_035280.1  galectin-3-binding protein precursor

      See identical proteins and their annotated locations for NP_035280.1

      Status: VALIDATED

      Source sequence(s)
      AK079915, BP765555
      Consensus CDS
      CCDS25701.1
      UniProtKB/Swiss-Prot
      O35649, Q07797, Q3U631, Q3U8K4, Q3UDL5
      Related
      ENSMUSP00000035579.4, ENSMUST00000043722.10
      Conserved Domains (3) summary
      smart00875
      Location:261358
      BACK; BTB And C-terminal Kelch
      smart00202
      Location:24124
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:29124
      SRCR; Scavenger receptor cysteine-rich domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      118283573..118292787 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156429.1XP_036012322.1  galectin-3-binding protein isoform X1

      Conserved Domains (3) summary
      smart00202
      Location:56156
      SR; Scavenger receptor Cys-rich
      cl38908
      Location:168279
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
      cl28903
      Location:288361
      BACK; BACK (BTB and C-terminal Kelch) domain