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    pof1b POF1B actin binding protein [ Danio rerio (zebrafish) ]

    Gene ID: 564098, updated on 2-Nov-2024

    Summary

    Official Symbol
    pof1bprovided by ZNC
    Official Full Name
    POF1B actin binding proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4287
    See related
    Ensembl:ENSDARG00000054060 AllianceGenome:ZFIN:ZDB-GENE-030131-4287
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc88b11; wu:fa99b01; wu:fc88b11; si:dkeyp-8h9.2
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; bicellular tight junction assembly; and epithelial cell morphogenesis. Predicted to be active in actin filament; adherens junction; and bicellular tight junction. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 2B. Orthologous to human POF1B (POF1B actin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See pof1b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (38513532..38581880, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (38465551..38534322, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene POU class 4 homeobox 4 Neighboring gene protein sprouty homolog 2 Neighboring gene solute carrier family 25 member 14 Neighboring gene G protein-coupled receptor 119

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in epithelial cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein POF1B
    Names
    premature ovarian failure, 1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      38513532..38581880 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068216131.1XP_068072232.1  protein POF1B isoform X1

      Related
      ENSDARP00000124164.2, ENSDART00000148939.3

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395097.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      326154..389957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068218980.1XP_068075081.1  protein POF1B isoform X1

    2. XM_002666059.7XP_002666105.6  protein POF1B isoform X2

    3. XM_068218979.1XP_068075080.1  protein POF1B isoform X2