slc25a26 solute carrier family 25 member 26 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc25a26provided by ZNC
Official Full Name: solute carrier family 25 member 26provided by ZNC
Primary source: ZFIN:ZDB-GENE-050913-126
See related: Ensembl:ENSDARG00000058208 AllianceGenome:ZFIN:ZDB-GENE-050913-126
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: SAMC; zgc:110080
Summary: Predicted to enable S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity. Predicted to be involved in mitochondrial S-adenosyl-L-methionine transmembrane transport. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Orthologous to human SLC25A26 (solute carrier family 25 member 26). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (16216935..16324575)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (16082300..16189940)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables S-adenosyl-L-methionine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables S-adenosyl-L-methionine transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables antiporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in S-adenosyl-L-methionine transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial S-adenosyl-L-methionine transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitochondrial S-adenosylmethionine carrier protein

Names: S-adenosylmethionine mitochondrial carrier protein; SAM carrier; mitochondrial S-adenosylmethionine transporter; solute carrier family 25 (S-adenosylmethionine carrier), member 26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030143.1 → NP_001025314.1 mitochondrial S-adenosylmethionine carrier protein

See identical proteins and their annotated locations for NP_001025314.1

Status: PROVISIONAL

Source sequence(s)

BC096793

UniProtKB/Swiss-Prot

Q4V9P0

UniProtKB/TrEMBL

B2GQ56

Related

ENSDARP00000075478.3, ENSDART00000081035.5

Conserved Domains (2) summary

PTZ00168
Location:5 → 258

PTZ00168; mitochondrial carrier protein; Provisional

pfam00153
Location:2 → 81

Mito_carr; Mitochondrial carrier protein