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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011510.1 RefSeqGene
- Range
-
5051..45379
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001001438.3 → NP_001001438.1 lanosterol synthase isoform 1
See identical proteins and their annotated locations for NP_001001438.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) represents the shortest transcript. Variants 1 and 2 encode the same protein (isoform 1).
- Source sequence(s)
-
AK312489, D63807
- Consensus CDS
-
CCDS13733.1
- UniProtKB/Swiss-Prot
- B4DJZ9, D3DSN0, E9PEI9, G5E9Q9, P48449, Q8IYL6, Q9UEZ1
- UniProtKB/TrEMBL
-
A0A384MTQ5
- Related
- ENSP00000348762.3, ENST00000356396.8
- Conserved Domains (1) summary
-
- TIGR01787
Location:76 → 721
- squalene_cyclas; squalene/oxidosqualene cyclases
-
NM_001145436.2 → NP_001138908.1 lanosterol synthase isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region and has a different 3' UTR, compared to variant 2. These differences result in a shorter protein (isoform 2), compared to isoform 1.
- Source sequence(s)
-
AK296313, AP001468, D63807
- Consensus CDS
-
CCDS46654.1
- UniProtKB/TrEMBL
-
A0A384MTQ5
- Related
- ENSP00000429133.1, ENST00000522411.5
- Conserved Domains (1) summary
-
- TIGR01787
Location:76 → 710
- squalene_cyclas; squalene/oxidosqualene cyclases
-
NM_001145437.2 → NP_001138909.1 lanosterol synthase isoform 3
See identical proteins and their annotated locations for NP_001138909.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) retains an intron segment between exons 1 and 2, compared to variant 2. This difference introduces a premature stop codon and results in the use of a downstream, in-frame start codon. The encoded protein (isoform 3) has a shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK226141, AP001468, D63807, DA333499
- Consensus CDS
-
CCDS54489.1
- UniProtKB/TrEMBL
-
A0A384MTQ5
- Related
- ENSP00000409191.2, ENST00000457828.6
- Conserved Domains (2) summary
-
- cd02892
Location:1 → 639
- SQCY_1; Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization ...
- TIGR01787
Location:1 → 641
- squalene_cyclas; squalene/oxidosqualene cyclases
-
NM_002340.6 → NP_002331.3 lanosterol synthase isoform 1
See identical proteins and their annotated locations for NP_002331.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) differs in the 3' UTR, compared to variant 2. Variants 1 and 2 encode the same protein (isoform 1).
- Source sequence(s)
-
AK312489, AP001468, D63807
- Consensus CDS
-
CCDS13733.1
- UniProtKB/Swiss-Prot
- B4DJZ9, D3DSN0, E9PEI9, G5E9Q9, P48449, Q8IYL6, Q9UEZ1
- UniProtKB/TrEMBL
-
A0A384MTQ5
- Related
- ENSP00000380837.2, ENST00000397728.8
- Conserved Domains (1) summary
-
- TIGR01787
Location:76 → 721
- squalene_cyclas; squalene/oxidosqualene cyclases
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000021.9 Reference GRCh38.p14 Primary Assembly
- Range
-
46188446..46228774 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_1
Genomic
-
NT_187626.1 Reference GRCh38.p14 ALT_REF_LOCI_1
- Range
-
49816..80959 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060945.1 Alternate T2T-CHM13v2.0
- Range
-
44570708..44611332 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)