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    ARPP21 cAMP regulated phosphoprotein 21 [ Homo sapiens (human) ]

    Gene ID: 10777, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ARPP21provided by HGNC
    Official Full Name
    cAMP regulated phosphoprotein 21provided by HGNC
    Primary source
    HGNC:HGNC:16968
    See related
    Ensembl:ENSG00000172995 MIM:605488; AllianceGenome:HGNC:16968
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RCS; TARPP; R3HDM3; ARPP-21
    Summary
    This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
    Expression
    Biased expression in brain (RPKM 4.3) and esophagus (RPKM 0.1) See more
    Orthologs
    mouse all
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    Genomic context

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    See ARPP21 in Genome Data Viewer
    Location:
    3p22.3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (35638853..35794486)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (35639532..35795160)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (35680345..35835978)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928135 Neighboring gene keratin 8 pseudogene 18 Neighboring gene RNA, U6 small nuclear 243, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:35496170-35496670 Neighboring gene NANOG hESC enhancer GRCh37_chr3:35524036-35524570 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr3:35546325-35546826 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr3:35546827-35547326 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19659 Neighboring gene ARPP21 antisense RNA 1 Neighboring gene microRNA 128-2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14194 Neighboring gene ribosomal protein L36a pseudogene 17 Neighboring gene replication factor C 3 pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia. Caporaso GL, et al. Neuropharmacology, 2000 Jul 10. PMID 10854908
    2. Mutation analysis of GLT8D1 and ARPP21 genes in amyotrophic lateral sclerosis patients from mainland China. Li W, et al. Neurobiol Aging, 2020 Jan. PMID 31653410
    3. Interstitial deletion of 3p22.3p22.2 encompassing ARPP21 and CLASP2 is a potential pathogenic factor for a syndromic form of intellectual disability: a co-morbidity model with additional copy number variations in a large family. Marangi G, et al. Am J Med Genet A, 2013 Nov. PMID 24127197
    4. Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis. Chan Moi Fat S, et al. Neurobiol Aging, 2021 May. PMID 33581934
    5. Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue. Brené S, et al. J Neurosci, 1994 Mar. PMID 8120638, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis.
      Title: Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis.
    2. Mutation analysis of GLT8D1 and ARPP21 genes in amyotrophic lateral sclerosis patients from mainland China.
      Title: Mutation analysis of GLT8D1 and ARPP21 genes in amyotrophic lateral sclerosis patients from mainland China.
    3. Interstitial deletion of 3p22.3p22.2 encompassing ARPP21 and CLASP2 is a potential pathogenic factor for a syndromic form of intellectual disability.
      Title: Interstitial deletion of 3p22.3p22.2 encompassing ARPP21 and CLASP2 is a potential pathogenic factor for a syndromic form of intellectual disability: a co-morbidity model with additional copy number variations in a large family.
    4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
    EBI GWAS Catalog
    Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.
    EBI GWAS Catalog

    Variation

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    See Variation Viewer (GRCh37.p13)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ32997

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cAMP-regulated phosphoprotein 21
    Names
    R3H domain containing 3
    cAMP regulated phosphoprotein 21kDa
    cyclic AMP-regulated phosphoprotein, 21 kD
    thymocyte cAMP-regulated phosphoprotein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_050660.1 RefSeqGene

      Range
      5352..160313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001025068.1 → NP_001020239.1  cAMP-regulated phosphoprotein 21 isoform 2

      See identical proteins and their annotated locations for NP_001020239.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses two alternate 5' exons and an alternate 3' exon compared to variant 1. The resulting isoform (2) has a distinct and much shorter C-terminus compared to isoform 1.
      Source sequence(s)
      AC016943, AV718064
      Consensus CDS
      CCDS43063.1
      UniProtKB/TrEMBL
      A0A024R2J2, A8K0T4, A8K1F3
      Related
      ENSP00000417838.1, ENST00000474696.5
      Conserved Domains (1) summary
      pfam14134
      Location:22 → 60
      DUF4301; Domain of unknown function (DUF4301)

    2. NM_001025069.1 → NP_001020240.1  cAMP-regulated phosphoprotein 21 isoform 2

      See identical proteins and their annotated locations for NP_001020240.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) uses two alternate 5' exons and an alternate 3' exon compared to variant 1. The resulting isoform (2) has a distinct and much shorter C-terminus compared to isoform 1.
      Source sequence(s)
      AC016943, AK055064, AV718064
      Consensus CDS
      CCDS43063.1
      UniProtKB/TrEMBL
      A0A024R2J2, A8K0T4, A8K1F3
      Related
      ENSP00000379742.2, ENST00000396482.6
      Conserved Domains (1) summary
      pfam14134
      Location:22 → 60
      DUF4301; Domain of unknown function (DUF4301)

    3. NM_001267616.2 → NP_001254545.1  cAMP-regulated phosphoprotein 21 isoform 2

      See identical proteins and their annotated locations for NP_001254545.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' and 3' UTR, lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC016943, BC036548, BC041385
      Consensus CDS
      CCDS43063.1
      UniProtKB/TrEMBL
      A0A024R2J2, A8K0T4, A8K1F3
      Related
      ENSP00000412411.1, ENST00000428373.5
      Conserved Domains (1) summary
      pfam14134
      Location:22 → 60
      DUF4301; Domain of unknown function (DUF4301)

    4. NM_001267617.2 → NP_001254546.1  cAMP-regulated phosphoprotein 21 isoform 3

      See identical proteins and their annotated locations for NP_001254546.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) contains a distinct 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The resulting isoform (3) is shorter, compared to isoform 1.
      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      UniProtKB/Swiss-Prot
      Q9UBL0
      Related
      ENSP00000405276.1, ENST00000444190.5
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    5. NM_001267618.2 → NP_001254547.1  cAMP-regulated phosphoprotein 21 isoform 2

      See identical proteins and their annotated locations for NP_001254547.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' and 3' UTR, lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC016943, AK289649, BC036548, DA275579
      Consensus CDS
      CCDS43063.1
      UniProtKB/TrEMBL
      A0A024R2J2, A8K0T4, A8K1F3
      Related
      ENSP00000390151.1, ENST00000412048.5
      Conserved Domains (1) summary
      pfam14134
      Location:22 → 60
      DUF4301; Domain of unknown function (DUF4301)

    6. NM_001267619.2 → NP_001254548.1  cAMP-regulated phosphoprotein 21 isoform 4

      See identical proteins and their annotated locations for NP_001254548.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) has a shorter 5' UTR and lacks two in-frame exons in the central coding region, compared to variant 1. The resulting isoform (4) is shorter, compared to isoform 1.
      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      UniProtKB/Swiss-Prot
      Q9UBL0
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    7. NM_001385484.1 → NP_001372413.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    8. NM_001385485.1 → NP_001372414.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    9. NM_001385486.1 → NP_001372415.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Related
      ENSP00000412326.1, ENST00000417925.5
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    10. NM_001385487.1 → NP_001372416.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    11. NM_001385488.1 → NP_001372417.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    12. NM_001385489.1 → NP_001372418.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    13. NM_001385490.1 → NP_001372419.1  cAMP-regulated phosphoprotein 21 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS93238.1
      UniProtKB/TrEMBL
      A0A804HI65
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:427 → 694
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:596 → 808
      gliding_GltJ; adventurous gliding motility protein GltJ

    14. NM_001385491.1 → NP_001372420.1  cAMP-regulated phosphoprotein 21 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:382 → 707
      Atrophin-1; Atrophin-1 family

    15. NM_001385492.1 → NP_001372421.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    16. NM_001385495.1 → NP_001372424.1  cAMP-regulated phosphoprotein 21 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:426 → 693
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:595 → 807
      gliding_GltJ; adventurous gliding motility protein GltJ

    17. NM_001385496.1 → NP_001372425.1  cAMP-regulated phosphoprotein 21 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:157 → 218
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:424 → 749
      Atrophin-1; Atrophin-1 family

    18. NM_001385497.1 → NP_001372426.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    19. NM_001385517.1 → NP_001372446.1  cAMP-regulated phosphoprotein 21 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:337 → 662
      Atrophin-1; Atrophin-1 family

    20. NM_001385536.1 → NP_001372465.1  cAMP-regulated phosphoprotein 21 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:449 → 774
      Atrophin-1; Atrophin-1 family

    21. NM_001385556.1 → NP_001372485.1  cAMP-regulated phosphoprotein 21 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:427 → 752
      Atrophin-1; Atrophin-1 family

    22. NM_001385558.1 → NP_001372487.1  cAMP-regulated phosphoprotein 21 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:407 → 674
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:576 → 788
      gliding_GltJ; adventurous gliding motility protein GltJ

    23. NM_001385562.1 → NP_001372491.1  cAMP-regulated phosphoprotein 21 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS93238.1
      UniProtKB/TrEMBL
      A0A804HI65
      Related
      ENSP00000506922.1, ENST00000684406.1
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:427 → 694
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:596 → 808
      gliding_GltJ; adventurous gliding motility protein GltJ

    24. NM_001385563.1 → NP_001372492.1  cAMP-regulated phosphoprotein 21 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:431 → 756
      Atrophin-1; Atrophin-1 family

    25. NM_001385564.1 → NP_001372493.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    26. NM_001385565.1 → NP_001372494.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    27. NM_001385566.1 → NP_001372495.1  cAMP-regulated phosphoprotein 21 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:161 → 222
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:428 → 753
      Atrophin-1; Atrophin-1 family

    28. NM_001385567.1 → NP_001372496.1  cAMP-regulated phosphoprotein 21 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:407 → 674
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:576 → 788
      gliding_GltJ; adventurous gliding motility protein GltJ

    29. NM_001385573.1 → NP_001372502.1  cAMP-regulated phosphoprotein 21 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:431 → 756
      Atrophin-1; Atrophin-1 family

    30. NM_001385574.1 → NP_001372503.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    31. NM_001385576.1 → NP_001372505.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    32. NM_001385577.1 → NP_001372506.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    33. NM_001385578.1 → NP_001372507.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    34. NM_001385580.1 → NP_001372509.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    35. NM_001385581.1 → NP_001372510.1  cAMP-regulated phosphoprotein 21 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58824.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    36. NM_001385582.1 → NP_001372511.1  cAMP-regulated phosphoprotein 21 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:431 → 756
      Atrophin-1; Atrophin-1 family

    37. NM_001385584.1 → NP_001372513.1  cAMP-regulated phosphoprotein 21 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:431 → 756
      Atrophin-1; Atrophin-1 family

    38. NM_001385585.1 → NP_001372514.1  cAMP-regulated phosphoprotein 21 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:449 → 774
      Atrophin-1; Atrophin-1 family

    39. NM_001385587.1 → NP_001372516.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    40. NM_001385588.2 → NP_001372517.1  cAMP-regulated phosphoprotein 21 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS58823.1
      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:450 → 775
      Atrophin-1; Atrophin-1 family

    41. NM_001385589.1 → NP_001372518.1  cAMP-regulated phosphoprotein 21 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:407 → 674
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:576 → 788
      gliding_GltJ; adventurous gliding motility protein GltJ

    42. NM_001385590.1 → NP_001372519.1  cAMP-regulated phosphoprotein 21 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:407 → 674
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:576 → 788
      gliding_GltJ; adventurous gliding motility protein GltJ

    43. NM_001385591.1 → NP_001372520.1  cAMP-regulated phosphoprotein 21 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:426 → 693
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:595 → 807
      gliding_GltJ; adventurous gliding motility protein GltJ

    44. NM_001385592.1 → NP_001372521.1  cAMP-regulated phosphoprotein 21 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS93238.1
      UniProtKB/TrEMBL
      A0A804HI65
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:427 → 694
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:596 → 808
      gliding_GltJ; adventurous gliding motility protein GltJ

    45. NM_001385593.1 → NP_001372522.1  cAMP-regulated phosphoprotein 21 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:427 → 694
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:596 → 808
      gliding_GltJ; adventurous gliding motility protein GltJ

    46. NM_001385594.1 → NP_001372523.1  cAMP-regulated phosphoprotein 21 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308
      Consensus CDS
      CCDS93238.1
      UniProtKB/TrEMBL
      A0A804HI65
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:427 → 694
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:596 → 808
      gliding_GltJ; adventurous gliding motility protein GltJ

    47. NM_001385595.1 → NP_001372524.1  cAMP-regulated phosphoprotein 21 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27) encodes the longest isoform (5).
      Source sequence(s)
      AC016943, AC104308
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    48. NM_016300.5 → NP_057384.2  cAMP-regulated phosphoprotein 21 isoform 1

      See identical proteins and their annotated locations for NP_057384.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AC016943, AC104308, BC051828
      Consensus CDS
      CCDS2661.1
      UniProtKB/Swiss-Prot
      B4DG96, Q49AK3, Q49AS6, Q4G0V4, Q6NYC3, Q86V31, Q9UBL0, Q9UF93
      Related
      ENSP00000187397.4, ENST00000187397.8
      Conserved Domains (3) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam11235
      Location:601 → 773
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain

    49. NM_198399.2 → NP_938409.1  cAMP-regulated phosphoprotein 21 isoform 2

      See identical proteins and their annotated locations for NP_938409.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate 5' exon and an alternate 3' exon compared to variant 1. The resulting isoform (2) has a distinct and much shorter C-terminus compared to isoform 1.
      Source sequence(s)
      AC016943, BC017805, BC036548
      Consensus CDS
      CCDS43063.1
      UniProtKB/TrEMBL
      A0A024R2J2, A8K0T4, A8K1F3
      Related
      ENSP00000379741.2, ENST00000396481.6

    RNA

    1. NR_169632.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    2. NR_169633.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    3. NR_169635.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    4. NR_169644.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    5. NR_169645.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    6. NR_169646.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    7. NR_169647.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    8. NR_170705.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    9. NR_170706.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    10. NR_170707.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC016943, AC104308

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      35638853..35794486
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011533303.4 → XP_011531605.1  cAMP-regulated phosphoprotein 21 isoform X1

      See identical proteins and their annotated locations for XP_011531605.1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    2. XM_017005580.3 → XP_016861069.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A804HI65
      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:427 → 694
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:596 → 808
      gliding_GltJ; adventurous gliding motility protein GltJ

    3. XM_017005598.3 → XP_016861087.1  cAMP-regulated phosphoprotein 21 isoform X8

      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:449 → 774
      Atrophin-1; Atrophin-1 family

    4. XM_011533299.4 → XP_011531601.1  cAMP-regulated phosphoprotein 21 isoform X1

      See identical proteins and their annotated locations for XP_011531601.1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    5. XM_017005584.3 → XP_016861073.1  cAMP-regulated phosphoprotein 21 isoform X4

      Conserved Domains (3) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam10631
      Location:543 → 648
      DUF2477; Protein of unknown function (DUF2477)
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain

    6. XM_017005591.3 → XP_016861080.1  cAMP-regulated phosphoprotein 21 isoform X6

      Conserved Domains (1) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

    7. XM_017005596.3 → XP_016861085.1  cAMP-regulated phosphoprotein 21 isoform X7

      Conserved Domains (1) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

    8. XM_017005574.3 → XP_016861063.1  cAMP-regulated phosphoprotein 21 isoform X1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    9. XM_047447338.1 → XP_047303294.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A804HI65

    10. XM_011533300.4 → XP_011531602.1  cAMP-regulated phosphoprotein 21 isoform X1

      See identical proteins and their annotated locations for XP_011531602.1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    11. XM_047447337.1 → XP_047303293.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A804HI65

    12. XM_047447339.1 → XP_047303295.1  cAMP-regulated phosphoprotein 21 isoform X3

    13. XM_047447340.1 → XP_047303296.1  cAMP-regulated phosphoprotein 21 isoform X6

    14. XM_024453320.2 → XP_024309088.1  cAMP-regulated phosphoprotein 21 isoform X1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    15. XM_024453322.2 → XP_024309090.1  cAMP-regulated phosphoprotein 21 isoform X5

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:407 → 674
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:576 → 788
      gliding_GltJ; adventurous gliding motility protein GltJ

    16. XM_024453323.2 → XP_024309091.1  cAMP-regulated phosphoprotein 21 isoform X9

      Conserved Domains (2) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      pfam03154
      Location:430 → 755
      Atrophin-1; Atrophin-1 family

    17. XM_011533302.4 → XP_011531604.1  cAMP-regulated phosphoprotein 21 isoform X1

      See identical proteins and their annotated locations for XP_011531604.1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    18. XM_017005575.3 → XP_016861064.1  cAMP-regulated phosphoprotein 21 isoform X1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    19. XM_017005590.3 → XP_016861079.1  cAMP-regulated phosphoprotein 21 isoform X5

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:407 → 674
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:576 → 788
      gliding_GltJ; adventurous gliding motility protein GltJ

    20. XM_011533301.4 → XP_011531603.1  cAMP-regulated phosphoprotein 21 isoform X1

      See identical proteins and their annotated locations for XP_011531603.1

      Conserved Domains (4) summary
      cd02642
      Location:163 → 224
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
      PHA03247
      Location:428 → 695
      PHA03247; large tegument protein UL36; Provisional
      pfam12752
      Location:245 → 300
      SUZ; SUZ domain
      NF033761
      Location:597 → 809
      gliding_GltJ; adventurous gliding motility protein GltJ

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      35639532..35795160
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054345011.1 → XP_054200986.1  cAMP-regulated phosphoprotein 21 isoform X1

    2. XM_054345019.1 → XP_054200994.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A804HI65

    3. XM_054345026.1 → XP_054201001.1  cAMP-regulated phosphoprotein 21 isoform X8

    4. XM_054345009.1 → XP_054200984.1  cAMP-regulated phosphoprotein 21 isoform X1

    5. XM_054345020.1 → XP_054200995.1  cAMP-regulated phosphoprotein 21 isoform X4

    6. XM_054345023.1 → XP_054200998.1  cAMP-regulated phosphoprotein 21 isoform X6

    7. XM_054345025.1 → XP_054201000.1  cAMP-regulated phosphoprotein 21 isoform X7

    8. XM_054345008.1 → XP_054200983.1  cAMP-regulated phosphoprotein 21 isoform X1

    9. XM_054345017.1 → XP_054200992.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A804HI65

    10. XM_054345010.1 → XP_054200985.1  cAMP-regulated phosphoprotein 21 isoform X1

    11. XM_054345016.1 → XP_054200991.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A804HI65

    12. XM_054345018.1 → XP_054200993.1  cAMP-regulated phosphoprotein 21 isoform X3

    13. XM_054345024.1 → XP_054200999.1  cAMP-regulated phosphoprotein 21 isoform X6

    14. XM_054345013.1 → XP_054200988.1  cAMP-regulated phosphoprotein 21 isoform X1

    15. XM_054345021.1 → XP_054200996.1  cAMP-regulated phosphoprotein 21 isoform X5

    16. XM_054345027.1 → XP_054201002.1  cAMP-regulated phosphoprotein 21 isoform X9

    17. XM_054345015.1 → XP_054200990.1  cAMP-regulated phosphoprotein 21 isoform X1

    18. XM_054345014.1 → XP_054200989.1  cAMP-regulated phosphoprotein 21 isoform X1

    19. XM_054345022.1 → XP_054200997.1  cAMP-regulated phosphoprotein 21 isoform X5

    20. XM_054345012.1 → XP_054200987.1  cAMP-regulated phosphoprotein 21 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UBL0.2 GenPept UniProtKB/Swiss-Prot:Q9UBL0

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