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    mllt3 MLLT3 super elongation complex subunit [ Danio rerio (zebrafish) ]

    Gene ID: 550517, updated on 28-Oct-2024

    Summary

    Official Symbol
    mllt3provided by ZNC
    Official Full Name
    MLLT3 super elongation complex subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-356
    See related
    Ensembl:ENSDARG00000006754 AllianceGenome:ZFIN:ZDB-GENE-050417-356
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc39c11; wu:fc39c11; zgc:110210
    Summary
    Predicted to enable chromatin binding activity and lysine-acetylated histone binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including digestive system; intermediate cell mass of mesoderm; nervous system; paraxial mesoderm; and pronephros. Orthologous to human MLLT3 (MLLT3 super elongation complex subunit). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
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    Genomic context

    See mllt3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (18779555..18881358, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (18527288..18629091, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:dkey-38l22.2 Neighboring gene tRNA methyltransferase 10A Neighboring gene focadhesin Neighboring gene zgc:194252 Neighboring gene C-type mannose receptor 2-like Neighboring gene 3-hydroxyacyl-CoA dehydratase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lysine-acetylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription elongation factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein AF-9
    Names
    myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog
    myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017819.1NP_001017819.1  protein AF-9

      See identical proteins and their annotated locations for NP_001017819.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092798
      UniProtKB/TrEMBL
      Q568M5
      Related
      ENSDARP00000004230.6, ENSDART00000021502.9
      Conserved Domains (1) summary
      pfam03366
      Location:177
      YEATS; YEATS family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      18779555..18881358 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477527.2XP_021333202.1  protein AF-9 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PNX3
      Conserved Domains (1) summary
      pfam03366
      Location:177
      YEATS; YEATS family
    2. XM_009303057.4XP_009301332.1  protein AF-9 isoform X1

      UniProtKB/TrEMBL
      A0A8M3BAV5
      Conserved Domains (1) summary
      pfam03366
      Location:29109
      YEATS; YEATS family