Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Tat
|
tat
|
Expression of HIV-1 Tat downregulates the abundance of tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (YWHAG, 14-3-3 gamma) in the nucleoli of Jurkat T-cells |
PubMed
|
Vpr
|
vpr
|
HIV-1 Vpr inhibits the binding of 14-3-3 gamma and AID to Smu and Sgamma1 DNA regions |
PubMed
|
|
vpr
|
HIV-1 Vpr inhibits insulin-induced association of 14-3-3 and Foxo3a in HeLa cells |
PubMed
|
|
vpr
|
Interaction of HIV-1 Vpr with human 14-3-3 protein is presumed based on homology to yeast DNA damage checkpoint protein rad25 which enhances HIV-1 Vpr-induced G2 arrest in vitro, most likely through the inhibition of Cdc25 |
PubMed
|
integrase
|
gag-pol
|
HIV-1 IN is identified to have a physical interaction with 14-3-3 gamma (YWHAG) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses |
PubMed
|
Go to the HIV-1, Human Interaction Database