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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_053187.2 RefSeqGene
- Range
-
60913..359665
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001282948.2 → NP_001269877.1 probable JmjC domain-containing histone demethylation protein 2C isoform c
See identical proteins and their annotated locations for NP_001269877.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (c, also known as s-JMJD1C) is shorter at the N-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c.
- Source sequence(s)
-
AL590502, AL607128, AL713895
- Consensus CDS
-
CCDS60538.1
- UniProtKB/TrEMBL
-
B7ZLC8
- Related
- ENSP00000444682.1, ENST00000542921.5
- Conserved Domains (3) summary
-
- smart00558
Location:2096 → 2168
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- pfam12067
Location:546 → 613
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2200 → 2299
- cupin_like; Conserved domain found in cupin and related proteins
-
NM_001318153.2 → NP_001305082.1 probable JmjC domain-containing histone demethylation protein 2C isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (d) is shorter at the N-terminus, compared to isoform a.
- Source sequence(s)
-
AL590502, AL607128, AL713895
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:1990 → 2062
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- pfam12067
Location:440 → 507
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2094 → 2193
- cupin_like; Conserved domain found in cupin and related proteins
-
NM_001318154.2 → NP_001305083.1 probable JmjC domain-containing histone demethylation protein 2C isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (c, also known as s-JMJD1C) is shorter at the N-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c.
- Source sequence(s)
-
AC022022, AL590502, AL607128, AL713895
- Consensus CDS
-
CCDS60538.1
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:2096 → 2168
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- pfam12067
Location:546 → 613
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2200 → 2299
- cupin_like; Conserved domain found in cupin and related proteins
-
NM_001322252.2 → NP_001309181.1 probable JmjC domain-containing histone demethylation protein 2C isoform e
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (e) that is shorter than isoform a.
- Source sequence(s)
-
AC022022, AL590502, AL713895
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:2240 → 2312
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- pfam12067
Location:690 → 757
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2344 → 2443
- cupin_like; Conserved domain found in cupin and related proteins
-
NM_001322254.2 → NP_001309183.1 probable JmjC domain-containing histone demethylation protein 2C isoform f
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (f) is shorter at the N-terminus, compared to isoform a. Both variants 8 and 9 encode isoform f.
- Source sequence(s)
-
AL590502, AL607128, AL713895
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:2059 → 2131
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- cl21464
Location:2163 → 2262
- cupin_like; Conserved domain found in cupin and related proteins
- cl26511
Location:88 → 453
- Neuromodulin_N; Gap junction protein N-terminal region
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NM_001322258.2 → NP_001309187.1 probable JmjC domain-containing histone demethylation protein 2C isoform f
Status: REVIEWED
- Description
- Transcript Variant: This variant (9) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (f) is shorter at the N-terminus, compared to isoform a. Both variants 8 and 9 encode isoform f.
- Source sequence(s)
-
AC022022, AL590502, AL607128, AL713895
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:2059 → 2131
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- cl21464
Location:2163 → 2262
- cupin_like; Conserved domain found in cupin and related proteins
- cl26511
Location:88 → 453
- Neuromodulin_N; Gap junction protein N-terminal region
-
NM_032776.3 → NP_116165.1 probable JmjC domain-containing histone demethylation protein 2C isoform a
See identical proteins and their annotated locations for NP_116165.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
AC022022, AL590502, AL607128, AL713895
- Consensus CDS
-
CCDS41532.1
- UniProtKB/Swiss-Prot
- A0T124, Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7
- UniProtKB/TrEMBL
-
B7ZLC8
- Related
- ENSP00000382204.2, ENST00000399262.7
- Conserved Domains (4) summary
-
- smart00558
Location:2278 → 2350
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- cd14798
Location:127 → 175
- RX-CC_like; Coiled-coil domain of the potato virux X resistance protein and similar proteins
- pfam12067
Location:728 → 795
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2382 → 2481
- cupin_like; Conserved domain found in cupin and related proteins
RNA
-
NR_134512.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) contains alternate 5' exon structure, lacks two internal exons, and uses two alternate splice sites, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, which is in-frame with the coding sequence of variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AL590502, AL607128, AL713895
- Related
-
ENST00000402544.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
63167225..63521890 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017015897.2 → XP_016871386.1 probable JmjC domain-containing histone demethylation protein 2C isoform X1
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:2096 → 2168
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- pfam12067
Location:546 → 613
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2200 → 2299
- cupin_like; Conserved domain found in cupin and related proteins
-
XM_047424773.1 → XP_047280729.1 probable JmjC domain-containing histone demethylation protein 2C isoform X1
-
XM_047424772.1 → XP_047280728.1 probable JmjC domain-containing histone demethylation protein 2C isoform X1
-
XM_047424774.1 → XP_047280730.1 probable JmjC domain-containing histone demethylation protein 2C isoform X2
-
XM_017015898.2 → XP_016871387.1 probable JmjC domain-containing histone demethylation protein 2C isoform X1
- UniProtKB/TrEMBL
-
B7ZLC8
- Conserved Domains (3) summary
-
- smart00558
Location:2096 → 2168
- JmjC; A domain family that is part of the cupin metalloenzyme superfamily
- pfam12067
Location:546 → 613
- Sox_C_TAD; Sox C-terminal transactivation domain
- cl21464
Location:2200 → 2299
- cupin_like; Conserved domain found in cupin and related proteins
-
XM_047424775.1 → XP_047280731.1 probable JmjC domain-containing histone demethylation protein 2C isoform X3
-
XM_011539508.3 → XP_011537810.1 probable JmjC domain-containing histone demethylation protein 2C isoform X4
- Conserved Domains (1) summary
-
- PTZ00121
Location:125 → 490
- PTZ00121; MAEBL; Provisional
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
64025342..64380031 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_004241.2: Suppressed sequence
- Description
- NM_004241.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.