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    acot18 acyl-CoA thioesterase 18 [ Danio rerio (zebrafish) ]

    Gene ID: 556673, updated on 2-Nov-2024

    Summary

    Official Symbol
    acot18provided by ZNC
    Official Full Name
    acyl-CoA thioesterase 18provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041210-254
    See related
    Ensembl:ENSDARG00000033413 AllianceGenome:ZFIN:ZDB-GENE-041210-254
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-183c16.7
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Is expressed in digestive system. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See acot18 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (25691642..25704068)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (25702444..25714870)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene peroxisomal succinyl-coenzyme A thioesterase-like Neighboring gene acyl-CoA thioesterase 16 Neighboring gene acyl-CoA thioesterase 17 Neighboring gene laminin, beta 1b Neighboring gene transmembrane and coiled-coil domain family 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001201537.1NP_001188466.1  acyl-CoA thioesterase 18

      Status: VALIDATED

      Source sequence(s)
      BX640593
      UniProtKB/TrEMBL
      A0A8M1NYX7, Q5RH35
      Related
      ENSDARP00000121203.1, ENSDART00000139053.3
      Conserved Domains (2) summary
      pfam04775
      Location:63189
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:253465
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      25691642..25704068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164824.5XP_005164881.1  acyl-CoA thioesterase 18 isoform X1

      See identical proteins and their annotated locations for XP_005164881.1

      UniProtKB/TrEMBL
      A0A8M2BC65, A8WG99, E9QBU5, F6NS28
      Related
      ENSDARP00000047112.6, ENSDART00000047113.6
      Conserved Domains (2) summary
      pfam04775
      Location:29155
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:219431
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394556.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      177975..189638
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)