psmc6 proteasome 26S subunit, ATPase 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmc6provided by ZNC
Official Full Name: proteasome 26S subunit, ATPase 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-304
See related: Ensembl:ENSDARG00000037038 AllianceGenome:ZFIN:ZDB-GENE-030131-304
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb20g04; wu:fb20g04; wu:fc85c10
Summary: Predicted to enable proteasome-activating activity. Predicted to be involved in ERAD pathway; positive regulation of RNA polymerase II transcription preinitiation complex assembly; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within proteolysis. Predicted to be part of cytosolic proteasome complex and proteasome regulatory particle, base subcomplex. Orthologous to human PSMC6 (proteasome 26S subunit, ATPase 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (9763377..9776329)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (9776137..9789089)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb20g04.x1 (e-PCR)
- UniSTS:203051

fc85c10.x1 (e-PCR)
- UniSTS:194648

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables proteasome-activating activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of RNA polymerase II transcription preinitiation complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of cytosolic proteasome complex	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle, base subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome regulatory subunit 10B

Names: 26S protease regulatory subunit S10B; proteasome (prosome, macropain) 26S subunit, ATPase, 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003832.1 → NP_001003832.1 26S proteasome regulatory subunit 10B

See identical proteins and their annotated locations for NP_001003832.1

Status: PROVISIONAL

Source sequence(s)

AY648827

UniProtKB/TrEMBL

A0A2R8PXV7, F6NTR1, Q6DRD2

Related

ENSDARP00000053833.3, ENSDART00000053834.5

Conserved Domains (2) summary

COG1222
Location:1 → 387

RPT1; ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones]

pfam00004
Location:171 → 303

AAA; ATPase family associated with various cellular activities (AAA)