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    ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a [ Danio rerio (zebrafish) ]

    Gene ID: 399487, updated on 12-Sep-2024

    Summary

    Official Symbol
    ywhaqaprovided by ZNC
    Official Full Name
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040122-5
    See related
    Ensembl:ENSDARG00000042539 AllianceGenome:ZFIN:ZDB-GENE-040122-5
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ywhaq; ywhaq2
    Summary
    Predicted to enable monooxygenase activity. Predicted to be involved in cellular protein localization and signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including immature eye; liver; nervous system; otic vesicle; and tail bud. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to several human genes including YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See ywhaqa in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (29565920..29585336)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29663041..29682457)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene Kruppel like factor 11a Neighboring gene TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B Neighboring gene ADAM metallopeptidase domain 17b Neighboring gene cleavage and polyadenylation specific factor 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
    Names
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201513.1NP_958921.1  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a

      See identical proteins and their annotated locations for NP_958921.1

      Status: PROVISIONAL

      Source sequence(s)
      BC048068
      UniProtKB/TrEMBL
      A8KC01, F6NNX8, Q7ZUM0
      Related
      ENSDARP00000062382.3, ENSDART00000062383.4
      Conserved Domains (1) summary
      cl02098
      Location:1233
      14-3-3; 14-3-3 domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      29565920..29585336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)