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    acin1b apoptotic chromatin condensation inducer 1b [ Danio rerio (zebrafish) ]

    Gene ID: 327495, updated on 2-Nov-2024

    Summary

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    Official Symbol
    acin1bprovided by ZNC
    Official Full Name
    apoptotic chromatin condensation inducer 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030826-12
    See related
    Ensembl:ENSDARG00000026842 AllianceGenome:ZFIN:ZDB-GENE-030826-12
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    acinus; acinusb; fi14c05; wu:fe06a10; wu:fi14c05
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in RNA splicing. Predicted to be part of ASAP complex. Orthologous to human ACIN1 (apoptotic chromatin condensation inducer 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See acin1b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24069420..24096259)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (23798167..23825102)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase (SDR family) member 4 Neighboring gene embryonal Fyn-associated substrate Neighboring gene small nucleolar RNA U6-53/MBII-28 Neighboring gene small nucleolar RNA U6-53/MBII-28 Neighboring gene small nucleolar RNA U6-53/MBII-28 Neighboring gene ajuba LIM protein Neighboring gene mitochondrial ribosomal protein L52

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. MNK2 deficiency potentiates β-cell regeneration via translational regulation. Karampelias C, et al. Nat Chem Biol, 2022 Sep. PMID 35697798, Free PMC Article
    2. Genes with homology to mammalian apoptosis regulators identified in zebrafish. Inohara N, et al. Cell Death Differ, 2000 May. PMID 10917738
    3. Processing of fish Ig heavy chain transcripts: diverse splicing patterns and unusual nonsense mediated decay. Quiniou SM, et al. Dev Comp Immunol, 2011 Sep. PMID 21168434
    4. Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates. Szenker-Ravi E, et al. Nat Genet, 2022 Jan. PMID 34903892
    5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ASAP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    apoptotic chromatin condensation inducer 1b
    Names
    apoptotic chromatin condensation inducer in the nucleus, b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305582.1 → NP_001292511.1  apoptotic chromatin condensation inducer 1b

      Status: VALIDATED

      Source sequence(s)
      CR388231, CT027785
      UniProtKB/TrEMBL
      A0A8M1P1U4, F1Q511
      Related
      ENSDARP00000029637.6, ENSDART00000034218.9
      Conserved Domains (3) summary
      cd12432
      Location:912 → 998
      RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
      pfam02037
      Location:14 → 48
      SAP; SAP domain
      pfam16294
      Location:1122 → 1157
      RSB_motif; RNSP1-SAP18 binding (RSB) motif

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24069420..24096259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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