kcnk1b potassium channel, subfamily K, member 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: kcnk1bprovided by ZNC
Official Full Name: potassium channel, subfamily K, member 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-090312-78
See related: Ensembl:ENSDARG00000017254 AllianceGenome:ZFIN:ZDB-GENE-090312-78
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-67f13.6
Summary: Enables potassium channel activity. Acts upstream of or within heart process. Predicted to be located in several cellular components, including perikaryon; recycling endosome; and synaptic membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain and heart. Orthologous to human KCNK1 (potassium two pore domain channel subfamily K member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 13

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (35856463..35872160)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (35730631..35746328)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables outward rectifier potassium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables potassium channel activity	IDA Inferred from Direct Assay more info	PubMed
enables potassium channel activity	IEA Inferred from Electronic Annotation more info
enables potassium ion leak channel activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within heart process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within heart process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in potassium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within potassium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within potassium ion transport	IEA Inferred from Electronic Annotation more info
involved_in stabilization of membrane potential	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in dendrite	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in perikaryon	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in recycling endosome	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info
located_in synaptic membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: potassium channel subfamily K member 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145575.1 → NP_001139047.1 potassium channel subfamily K member 1b isoform 2

Status: VALIDATED

Source sequence(s)

FQ482151

UniProtKB/TrEMBL

A0A0R4IHS3, A0A8M1NQ28

Related

ENSDARP00000133254.1, ENSDART00000171056.2
NM_001290348.1 → NP_001277277.1 potassium channel subfamily K member 1b isoform 1

Status: VALIDATED

Source sequence(s)

FQ482151

UniProtKB/TrEMBL

A0A8M1P6I7, B8A573

Related

ENSDARP00000006324.6, ENSDART00000017202.8

Conserved Domains (1) summary

pfam07885
Location:99 → 157

Ion_trans_2; Ion channel