fgf13a fibroblast growth factor 13a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fgf13aprovided by ZNC
Official Full Name: fibroblast growth factor 13aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-101
See related: Ensembl:ENSDARG00000035056 AllianceGenome:ZFIN:ZDB-GENE-041114-101
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fgf13; zgc:101784
Summary: Predicted to enable sodium channel regulator activity. Predicted to be involved in neurogenesis and regulation of voltage-gated sodium channel activity. Predicted to act upstream of or within nervous system development. Predicted to be located in several cellular components, including filopodium; growth cone; and sarcolemma. Predicted to be active in cytoplasm and nucleus. Is expressed in basal plate midbrain region; heart; myotome; nervous system; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 90 and non-syndromic X-linked intellectual disability. Orthologous to human FGF13 (fibroblast growth factor 13). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 14

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (32183978..32403640, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (31843673..32064845, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

G45862 (e-PCR)
- UniSTS:106664

fc10b06.x1 (e-PCR)
- UniSTS:192428

fj04c09.x1 (e-PCR)
- UniSTS:198350

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables growth factor activity	IEA Inferred from Electronic Annotation more info
enables sodium channel regulator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within nervous system development	IEA Inferred from Electronic Annotation more info
involved_in neurogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of voltage-gated sodium channel activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in dendrite	IEA Inferred from Electronic Annotation more info
located_in filopodium	IEA Inferred from Electronic Annotation more info
located_in growth cone	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in sarcolemma	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: fibroblast growth factor 13a

Names: fibroblast growth factor 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.