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    mala.2 mal, T cell differentiation protein a, tandem duplicate 2 [ Danio rerio (zebrafish) ]

    Gene ID: 768299, updated on 2-Nov-2024

    Summary

    Official Symbol
    mala.2provided by ZNC
    Official Full Name
    mal, T cell differentiation protein a, tandem duplicate 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061027-365
    See related
    Ensembl:ENSDARG00000043442 AllianceGenome:ZFIN:ZDB-GENE-061027-365
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb11f04; zgc:153665
    Summary
    Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human MAL (mal, T cell differentiation protein). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See mala.2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (30630905..30634248, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (30383719..30388974, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 178a Neighboring gene solute carrier family 8 member 1a Neighboring gene mal, T cell differentiation protein a, tandem duplicate 1 Neighboring gene post-GPI attachment to proteins GalNAc transferase 4 Neighboring gene two pore segment channel 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC153665

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of myelin sheath IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in myelination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC768299

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077463.1NP_001070931.1  uncharacterized protein LOC768299

      See identical proteins and their annotated locations for NP_001070931.1

      Status: PREDICTED

      Source sequence(s)
      BC124417
      UniProtKB/TrEMBL
      Q05AL4
      Related
      ENSDARP00000150298.1, ENSDART00000191019.1
      Conserved Domains (1) summary
      pfam01284
      Location:18146
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      30630905..30634248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)