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    akap6 A kinase (PRKA) anchor protein 6 [ Danio rerio (zebrafish) ]

    Gene ID: 100002625, updated on 17-Sep-2024

    Summary

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    Official Symbol
    akap6provided by ZNC
    Official Full Name
    A kinase (PRKA) anchor protein 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-120207-2
    See related
    Ensembl:ENSDARG00000077295 AllianceGenome:ZFIN:ZDB-GENE-120207-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Human ortholog(s) of this gene implicated in anorexia nervosa and ovary epithelial cancer. Orthologous to human AKAP6 (A-kinase anchoring protein 6). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See akap6 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (8988374..9266845)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (8831200..9109665)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene proteasome 26S subunit, ATPase 1a Neighboring gene zinc finger, RAN-binding domain containing 1b Neighboring gene neuronal PAS domain protein 3 Neighboring gene uncharacterized LOC108179743 Neighboring gene uncharacterized LOC103909016

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish Nk-lysins: First insights about their cellular and functional diversification. Pereiro P, et al. Dev Comp Immunol, 2015 Jul. PMID 25813149
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    A-kinase anchor protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      8988374..9266845
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001919913.8 → XP_001919948.3  A-kinase anchor protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A8M1QHB1, F1QAQ3
      Related
      ENSDARP00000100004.2, ENSDART00000109573.3
      Conserved Domains (2) summary
      cd00176
      Location:839 → 1082
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02488
      Location:666 → 864
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    2. XM_021467296.2 → XP_021322971.1  A-kinase anchor protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A2R8PW09, A0A8M9PL25
      Related
      ENSDARP00000145038.1, ENSDART00000186901.1
      Conserved Domains (2) summary
      cl02488
      Location:666 → 864
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl25732
      Location:604 → 1012
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_021467295.2 → XP_021322970.1  A-kinase anchor protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PP43
      Related
      ENSDARP00000152756.1, ENSDART00000180856.1
      Conserved Domains (2) summary
      cd00176
      Location:838 → 1081
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl25732
      Location:604 → 1020
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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