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    slc15a4 solute carrier family 15 member 4 [ Danio rerio (zebrafish) ]

    Gene ID: 393932, updated on 12-Sep-2024

    Summary

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    Official Symbol
    slc15a4provided by ZNC
    Official Full Name
    solute carrier family 15 member 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1047
    See related
    Ensembl:ENSDARG00000102612 AllianceGenome:ZFIN:ZDB-GENE-040426-1047
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    bZ1L10.1; zgc:56484; zgc:63767
    Summary
    Predicted to enable symporter activity. Predicted to act upstream of or within oligopeptide transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in epidermis; immature eye; nervous system; periderm; and yolk syncytial layer. Orthologous to several human genes including SLC15A4 (solute carrier family 15 member 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See slc15a4 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (35809055..35961008, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (36079707..36231660, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496372 Neighboring gene si:dkeyp-14d3.1 Neighboring gene uncharacterized LOC110438828 Neighboring gene glycosyltransferase 1 domain containing 1 Neighboring gene transmembrane protein 132D Neighboring gene major histocompatibility complex class II d8.35a1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56484

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dipeptide import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within oligopeptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 15 member 4
    Names
    bZ1L10.1 (novel peptide transporter)
    solute carrier family 15 (oligopeptide transporter), member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001320529.1 → NP_001307458.1  solute carrier family 15 member 4

      Status: VALIDATED

      Source sequence(s)
      AL627256, CU693378
      UniProtKB/TrEMBL
      A0A0R4ICA5, A0A8M1P8Q5
      Related
      ENSDARP00000132430.1, ENSDART00000160503.2
      Conserved Domains (1) summary
      cl21472
      Location:158 → 522
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      35809055..35961008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_200957.1: Suppressed sequence

      Description
      NM_200957.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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