oxct1a 3-oxoacid CoA transferase 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: oxct1aprovided by ZNC
Official Full Name: 3-oxoacid CoA transferase 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040723-3
See related: Ensembl:ENSDARG00000013063 AllianceGenome:ZFIN:ZDB-GENE-040723-3
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: oxct1; zgc:92003; wu:fj36f06; wu:fj48g08
Summary: Predicted to enable succinyl-CoA:3-oxo-acid CoA-transferase activity. Predicted to be involved in cellular ketone body metabolic process. Predicted to act upstream of or within ketone body catabolic process. Predicted to be active in mitochondrion. Is expressed in somite. Orthologous to several human genes including OXCT1 (3-oxoacid CoA-transferase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (31717304..31818461)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (31708072..31809229)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj48g08.x1 (e-PCR)
- UniSTS:199440

fj36f06.x1 (e-PCR)
- UniSTS:188484

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables CoA-transferase activity	IEA Inferred from Electronic Annotation more info
enables succinyl-CoA:3-oxo-acid CoA-transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables succinyl-CoA:3-oxo-acid CoA-transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellular ketone body metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ketone body catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

Names: 3-oxoacid CoA transferase 1; SAGm18B; sagm18c; scot

NP_001007292.1

EC 2.8.3.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007291.1 → NP_001007292.1 succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

See identical proteins and their annotated locations for NP_001007292.1

Status: PROVISIONAL

Source sequence(s)

BC078408

UniProtKB/TrEMBL

B2GNI2, Q6AZB2

Related

ENSDARP00000002234.9, ENSDART00000013434.11

Conserved Domains (3) summary

COG1788
Location:55 → 277

AtoD; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid transport and metabolism]

COG4670
Location:55 → 524

YdiF; Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism]

cl00339
Location:308 → 515

SugarP_isomerase; SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ...