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    ubxn1 UBX domain protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 322073, updated on 28-Oct-2024

    Summary

    Official Symbol
    ubxn1provided by ZNC
    Official Full Name
    UBX domain protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-792
    See related
    Ensembl:ENSDARG00000090309 AllianceGenome:ZFIN:ZDB-GENE-030131-792
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb49a05; zgc:77531; wu:fb49a05
    Summary
    Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity and K6-linked polyubiquitin modification-dependent protein binding activity. Predicted to be involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein K48-linked deubiquitination; and negative regulation of protein ubiquitination. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBXN1 (UBX domain protein 1). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
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    Genomic context

    See ubxn1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (45471736..45482605)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (46484417..46495313)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene EH-domain containing 1a Neighboring gene microRNA 194b Neighboring gene si:ch211-114c17.1 Neighboring gene glucosidase II alpha subunit b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables K48-linked polyubiquitin modification-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables K6-linked polyubiquitin modification-dependent protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    UBX domain-containing protein 1
    Names
    SAPK substrate protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212607.1NP_997772.1  UBX domain-containing protein 1

      See identical proteins and their annotated locations for NP_997772.1

      Status: PROVISIONAL

      Source sequence(s)
      BC067166
      UniProtKB/Swiss-Prot
      Q6NXA9
      Related
      ENSDARP00000108064.1, ENSDART00000126979.4
      Conserved Domains (2) summary
      cd01772
      Location:215293
      SAKS1_UBX; SAKS1-like UBX domain
      cd14302
      Location:545
      UBA_UBXN1; UBA domain found in UBX domain-containing protein 1 (UBXN1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      45471736..45482605
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)