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    ppp1r9alb protein phosphatase 1 regulatory subunit 9A-like B [ Danio rerio (zebrafish) ]

    Gene ID: 100007681, updated on 28-Oct-2024

    Summary

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    Official Symbol
    ppp1r9albprovided by ZNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 9A-like Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090312-99
    See related
    Ensembl:ENSDARG00000074575 AllianceGenome:ZFIN:ZDB-GENE-090312-99
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-269i23.2
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; calcium-mediated signaling; and neuron projection development. Predicted to act upstream of or within nervous system development. Predicted to be located in cytoskeleton. Predicted to be active in several cellular components, including actin cytoskeleton; dendrite; and postsynaptic density. [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See ppp1r9alb in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (31071707..31105427, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (30267753..30301453, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene distal-less homeobox 2b Neighboring gene integrin, alpha 6b Neighboring gene uncharacterized LOC137495535 Neighboring gene eukaryotic translation elongation factor 1 alpha 1b Neighboring gene potassium voltage-gated channel, KQT-like subfamily, member 5b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. Takeuchi M, et al. J Comp Neurol, 2017 May 1. PMID 27615194
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    KS5 protein; neurabin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      31071707..31105427 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221367.1 → XP_068077468.1  neurabin-1 isoform X2

    2. XM_068221373.1 → XP_068077474.1  neurabin-1 isoform X3

      Related
      ENSDARP00000123505.2, ENSDART00000132466.5

    3. XM_009292002.4 → XP_009290277.1  neurabin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q9W9
      Conserved Domains (3) summary
      cd09512
      Location:1378 → 1447
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      cd00992
      Location:661 → 744
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl25732
      Location:800 → 998
      SMC_N; RecF/RecN/SMC N terminal domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394493.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      227779..261301 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021471211.2 → XP_021326886.1  neurabin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PX85
      Conserved Domains (3) summary
      cd09512
      Location:1378 → 1447
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      cd00992
      Location:661 → 744
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl25732
      Location:798 → 998
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_068218013.1 → XP_068074114.1  neurabin-1 isoform X2

    3. XM_068218014.1 → XP_068074115.1  neurabin-1 isoform X3

    4. XM_068218012.1 → XP_068074113.1  neurabin-1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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