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    puf60b poly-U binding splicing factor b [ Danio rerio (zebrafish) ]

    Gene ID: 415211, updated on 2-Nov-2024

    Summary

    Official Symbol
    puf60bprovided by ZNC
    Official Full Name
    poly-U binding splicing factor bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-116
    See related
    Ensembl:ENSDARG00000001241 AllianceGenome:ZFIN:ZDB-GENE-040625-116
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    SIAHBP1; fe37c05; repressor; zgc:86806; wu:fb33e11; wu:fe37c05; si:zc12p8.2; si:ch211-12p8.2
    Summary
    Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome; mRNA splice site recognition; and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing; apoptotic process; and mRNA processing. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Is expressed in endocrine system; nervous system; pectoral fin; pharynx; and somite. Orthologous to human PUF60 (poly(U) binding splicing factor 60). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See puf60b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (41146612..41158142)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (40866513..40878069)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496190 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b Neighboring gene scribble planar cell polarity protein Neighboring gene kinesin family member 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    poly(U)-binding-splicing factor PUF60-B
    Names
    fuse-binding protein-interacting repressor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002121.2NP_001002121.2  poly(U)-binding-splicing factor PUF60-B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL772146
      Related
      ENSDARP00000052273.4, ENSDART00000052274.5
    2. NM_001430966.1NP_001417895.1  poly(U)-binding-splicing factor PUF60-B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL772146
      UniProtKB/TrEMBL
      A0A2R8RVR3, A0A8M3AUG9
      Related
      ENSDARP00000153956.1, ENSDART00000185388.1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      41146612..41158142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)