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    bora bora aurora kinase A activator [ Danio rerio (zebrafish) ]

    Gene ID: 555606, updated on 28-Oct-2024

    Summary

    Official Symbol
    boraprovided by ZNC
    Official Full Name
    bora aurora kinase A activatorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-165
    See related
    Ensembl:ENSDARG00000042688 AllianceGenome:ZFIN:ZDB-GENE-041114-165
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101616
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be involved in regulation of mitotic nuclear division; regulation of mitotic spindle organization; and regulation of protein localization. Predicted to act upstream of or within cell division. Predicted to be active in cytoplasm and nucleus. Is expressed in alar plate midbrain region; nervous system; optic vesicle; pharyngeal arch; and yolk syncytial layer. Orthologous to human BORA (BORA aurora kinase A activator). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    NEW
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    Genomic context

    See bora in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (30723411..30734803)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (29919455..29930872)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene dachshund c Neighboring gene mitotic spindle organizing protein 1 Neighboring gene DIS3 exosome endoribonuclease and 3'-5' exoribonuclease Neighboring gene methionyl aminopeptidase type 1D (mitochondrial)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC101616, MGC173752

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of mitotic nuclear division ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of mitotic spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of mitotic spindle organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein aurora borealis
    Names
    aurora borealis

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007450.1NP_001007451.1  protein aurora borealis

      See identical proteins and their annotated locations for NP_001007451.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085389
      UniProtKB/Swiss-Prot
      Q5U3U6
      UniProtKB/TrEMBL
      B7ZV92
      Related
      ENSDARP00000110650.2, ENSDART00000127670.3
      Conserved Domains (1) summary
      pfam15280
      Location:5198
      BORA_N; Protein aurora borealis N-terminus

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      30723411..30734803
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159946.5XP_005160003.1  protein aurora borealis isoform X1

      See identical proteins and their annotated locations for XP_005160003.1

      UniProtKB/TrEMBL
      A0A8M2B6S6, F1QD62
      Related
      ENSDARP00000062627.6, ENSDART00000062628.8
      Conserved Domains (1) summary
      pfam15280
      Location:5198
      BORA_N; Protein aurora borealis N-terminus

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394492.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      165561..176472
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)