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    tmeff1b transmembrane protein with EGF-like and two follistatin-like domains 1b [ Danio rerio (zebrafish) ]

    Gene ID: 553511, updated on 2-Nov-2024

    Summary

    Official Symbol
    tmeff1bprovided by ZNC
    Official Full Name
    transmembrane protein with EGF-like and two follistatin-like domains 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050706-143
    See related
    Ensembl:ENSDARG00000056740 AllianceGenome:ZFIN:ZDB-GENE-050706-143
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tmeff1; fb53c10; wu:fb53c10; zgc:110069
    Summary
    Predicted to be involved in cell differentiation. Predicted to be located in membrane. Predicted to be active in extracellular region. Orthologous to several human genes including TMEFF1 (transmembrane protein with EGF like and two follistatin like domains 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See tmeff1b in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (33708804..33756003, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (33822629..33869828, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene dynein, axonemal, heavy chain 5 like Neighboring gene golgin subfamily A member 6-like protein 24 Neighboring gene caveolae associated protein 4b Neighboring gene cyclin dependent kinase 5 Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC110069

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tomoregulin-1b
    Names
    transmembrane protein with EGF-like and two follistatin-like domains 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025301.1NP_001020472.1  tomoregulin-1b

      See identical proteins and their annotated locations for NP_001020472.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098543
      UniProtKB/TrEMBL
      Q4KMI9
      Related
      ENSDARP00000073739.5, ENSDART00000079283.6
      Conserved Domains (2) summary
      PHA02887
      Location:263300
      PHA02887; EGF-like protein; Provisional
      smart00280
      Location:89134
      KAZAL; Kazal type serine protease inhibitors

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      33708804..33756003 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)