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    taf8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor [ Danio rerio (zebrafish) ]

    Gene ID: 393256, updated on 2-Nov-2024

    Summary

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    Official Symbol
    taf8provided by ZNC
    Official Full Name
    TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1013
    See related
    Ensembl:ENSDARG00000026806 AllianceGenome:ZFIN:ZDB-GENE-040426-1013
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tbnl; zgc:56401; zgc:77837
    Summary
    Predicted to enable protein heterodimerization activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to act upstream of or within cell differentiation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF8 (TATA-box binding protein associated factor 8). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See taf8 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (32392461..32401225)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (32465919..32474461)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 5 Neighboring gene ankyrin repeat domain 52a Neighboring gene si:ch211-66i15.4 Neighboring gene si:ch211-66i15.5 Neighboring gene transcription initiation factor TFIID subunit 8-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Burket CT, et al. Transgenic Res, 2008 Apr. PMID 17968670, Free PMC Article
    2. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56401

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    transcription initiation factor TFIID subunit 8
    Names
    TBP-associated factor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200286.1 → NP_956580.1  transcription initiation factor TFIID subunit 8

      See identical proteins and their annotated locations for NP_956580.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049422
      UniProtKB/Swiss-Prot
      Q6P0T2
      Related
      ENSDARP00000130755.2, ENSDART00000171715.2
      Conserved Domains (2) summary
      cd08049
      Location:146 → 199
      TAF8; TATA Binding Protein (TBP) Associated Factor 8
      pfam07524
      Location:32 → 108
      Bromo_TP; Bromodomain associated

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      32392461..32401225
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162303.5 → XP_005162360.1  transcription initiation factor TFIID subunit 8 isoform X1

      See identical proteins and their annotated locations for XP_005162360.1

      UniProtKB/Swiss-Prot
      Q6P0T2, Q7ZWG5
      Related
      ENSDARP00000032165.8, ENSDART00000039498.10
      Conserved Domains (2) summary
      cd08049
      Location:146 → 199
      TAF8; TATA Binding Protein (TBP) Associated Factor 8
      pfam07524
      Location:32 → 108
      Bromo_TP; Bromodomain associated

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395161.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      358393..366843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P0T2.1 GenPept UniProtKB/Swiss-Prot:Q6P0T2

    Gene LinkOut

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