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    tpr1 RNA polymerase II-associated Paf1 complex subunit Tpr1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542077, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tpr1
    Official Full Name
    RNA polymerase II-associated Paf1 complex subunit Tpr1
    Primary source
    PomBase:SPAC27D7.14c
    Locus tag
    SPOM_SPAC27D7.14C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ctr9; SPAC637.02c
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    Genomic context

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    See tpr1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4536975..4540359, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene thioredoxin family protein But1 Neighboring gene ncRNA Neighboring gene dynactin microtubule-binding subunit, p150-Glued Ssm4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spt5 Phosphorylation and the Rtf1 Plus3 Domain Promote Rtf1 Function through Distinct Mechanisms. Chen JJ, et al. Mol Cell Biol, 2020 Jul 14. PMID 32366382, Free PMC Article
    2. Global regulation of heterochromatin spreading by Leo1. Verrier L, et al. Open Biol, 2015 May. PMID 25972440, Free PMC Article
    3. The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast. Mbogning J, et al. PLoS Genet, 2013. PMID 24385927, Free PMC Article
    4. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
    5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription elongation by RNA polymerase I ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription elongation by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Cdc73/Paf1 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    RNA polymerase II-associated Paf1 complex subunit Tpr1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4536975..4540359 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020048.3 → NP_594620.1  RNA polymerase II-associated Paf1 complex subunit Tpr1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594620.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42668, O42796
      Conserved Domains (7) summary
      TIGR02795
      Location:299 → 389
      tol_pal_ybgF; tol-pal system protein YbgF
      sd00006
      Location:667 → 696
      TPR; TPR repeat [structural motif]
      pfam13181
      Location:326 → 356
      TPR_8; Tetratricopeptide repeat
      pfam13414
      Location:174 → 241
      TPR_11; TPR repeat
      pfam13424
      Location:664 → 729
      TPR_12; Tetratricopeptide repeat
      pfam14138
      Location:875 → 916
      COX16; Cytochrome c oxidase assembly protein COX16
      cl23849
      Location:793 → 916
      TrbI; Bacterial conjugation TrbI-like protein
    Nucleotide Protein
    Heading Accession and Version

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