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    PUN1 Pun1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851132, updated on 29-Jun-2024

    Summary

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    Gene symbol
    PUN1
    Gene description
    Pun1p
    Primary source
    FungiDB:YLR414C
    Locus tag
    YLR414C
    See related
    SGD:S000004406; AllianceGenome:SGD:S000004406; VEuPathDB:YLR414C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in fungal-type cell wall organization. Located in plasma membrane. Colocalizes with eisosome. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PUN1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (953353..954144, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ina1p Neighboring gene uncharacterized protein Neighboring gene ESCRT-II subunit protein VPS36

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pun1p is a metal ion-inducible, calcineurin/Crz1p-regulated plasma membrane protein required for cell wall integrity. Hosiner D, et al. Biochim Biophys Acta, 2011 Apr. PMID 21223946, Free PMC Article
    2. A profile of differentially abundant proteins at the yeast cell periphery during pseudohyphal growth. Xu T, et al. J Biol Chem, 2010 May 14. PMID 20228058, Free PMC Article
    3. The 'yeast cell wall chip' - a tool to analyse the regulation of cell wall biogenesis in Saccharomyces cerevisiae. Rodríguez-Peña JM, et al. Microbiology (Reading), 2005 Jul. PMID 16000714
    4. The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans. Alvarez FJ, et al. Mol Biol Cell, 2008 Dec. PMID 18799621, Free PMC Article
    5. Ssd1 is required for thermotolerance and Hsp104-mediated protein disaggregation in Saccharomyces cerevisiae. Mir SS, et al. Mol Cell Biol, 2009 Jan. PMID 18936161, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell cortex of cell tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell periphery HDA PubMed 
    located_in cellular bud HDA PubMed 
    located_in cytoplasm HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pun1p
    NP_013518.3
    • Plasma membrane protein with a role in cell wall integrity; co-localizes with Sur7p in punctate membrane patches; null mutant displays decreased thermotolerance; transcription induced upon cell wall damage and metal ion stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      953353..954144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182302.3 → NP_013518.3  TPA: Pun1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013518.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ51, Q06991, Q6B322
      UniProtKB/TrEMBL
      A0A8H4BXJ9, A7A1T7, B3RHS5, C7GXL6, C8ZE23, G2WJM8, N1P7E0
      Conserved Domains (1) summary
      pfam06687
      Location:6 → 240
      SUR7; SUR7/PalI family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06991.1

    Gene LinkOut

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