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    FAM156A family with sequence similarity 156 member A [ Homo sapiens (human) ]

    Gene ID: 29057, updated on 2-Nov-2024

    Summary

    Official Symbol
    FAM156Aprovided by HGNC
    Official Full Name
    family with sequence similarity 156 member Aprovided by HGNC
    Primary source
    HGNC:HGNC:30114
    See related
    Ensembl:ENSG00000268350 AllianceGenome:HGNC:30114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TMEM29; PRO0659
    Summary
    Predicted to enable methylated histone binding activity. Located in nuclear envelope. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in skin (RPKM 15.8), placenta (RPKM 14.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See FAM156A in Genome Data Viewer
    Location:
    Xp11.22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (52947254..52995472, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (52231792..52279984, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (52976462..53024651, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 156 member B Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:52949629-52950232 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29646 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29647 Neighboring gene uncharacterized LOC124905190 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29649 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:52963212-52964184 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:52964185-52965156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:53018839-53019418 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:53045322-53045423 Neighboring gene G protein-coupled receptor 173 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:53100667-53101168 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29651 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20852 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20853 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20854 Neighboring gene TSPY like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    General gene information

    Clone Names

    • DKFZp686B22211

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables methylated histone binding  
    enables protein binding PubMed 
    Component Evidence Code Pubs
    located_in membrane  
    located_in nuclear envelope  

    General protein information

    Preferred Names
    protein FAM156A/FAM156B
    Names
    protein FAM156A
    transmembrane protein 29
    transmembrane protein 29/29B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242489.2NP_001229418.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229418.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      AK057692, BC000867, DA685609, DA849151
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000479184.1, ENST00000615092.4
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    2. NM_001242490.2NP_001229419.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229419.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      BC000867, BU192418, DA347198, DA572135
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000477905.2, ENST00000622323.5
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    3. NM_001242491.1NP_001229420.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229420.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      AK057692, BC000867, DA371625
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000481435.1, ENST00000617970.4
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    4. NM_001242492.2NP_001229421.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229421.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      BC000867, BC067819, BI829697, DA685609
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000485247.1, ENST00000623782.3
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    5. NM_001242493.2NP_001229422.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229422.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      BC000867, DA347198, DA572135, DA691898
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000484967.2, ENST00000612083.5
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    6. NM_001242494.2NP_001229423.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229423.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      BC000867, DA347198, DA685609
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    7. NM_001242495.2NP_001229424.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229424.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      BC000867, BC067819, DA685609
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000480518.1, ENST00000611661.4
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    8. NM_001242496.2NP_001229425.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229425.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      BC000867, BC067819, CB139342, DA572135
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000484757.2, ENST00000619373.5
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    9. NM_001242497.2NP_001229426.1  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_001229426.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
      Source sequence(s)
      AF090943, DA368012, DA572135
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000479338.2, ENST00000622732.5
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    10. NM_001377060.1NP_001363989.1  protein FAM156A/FAM156B

      Status: VALIDATED

      Source sequence(s)
      AC234031
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000471676.1, ENST00000596733.7
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    11. NM_001377061.1NP_001363990.1  protein FAM156A/FAM156B

      Status: VALIDATED

      Source sequence(s)
      AC234031
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000482562.2, ENST00000619518.5
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    12. NM_001377062.1NP_001363991.1  protein FAM156A/FAM156B

      Status: VALIDATED

      Source sequence(s)
      AC234031
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    13. NM_001377063.1NP_001363992.1  protein FAM156A/FAM156B

      Status: VALIDATED

      Source sequence(s)
      AC234031
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000480373.1, ENST00000613284.1
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    14. NM_001387706.1NP_001374635.1  protein FAM156A/FAM156B

      Status: VALIDATED

      Source sequence(s)
      AC234031
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000482142.1, ENST00000622447.5
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    15. NM_014138.5NP_054857.2  protein FAM156A/FAM156B

      See identical proteins and their annotated locations for NP_054857.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-10 encode the same protein.
      Source sequence(s)
      AK057692, BC000867, DA256347, DA572135
      Consensus CDS
      CCDS35297.1
      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Related
      ENSP00000484167.1, ENST00000612915.4
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      52947254..52995472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017029457.1XP_016884946.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      UniProtKB/TrEMBL
      A0A087WVC8
      Conserved Domains (1) summary
      pfam15549
      Location:1170
      PGC7_Stella; PGC7/Stella/Dppa3 domain
    2. XM_047442036.1XP_047297992.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    3. XM_047442034.1XP_047297990.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      Related
      ENSP00000482980.2, ENST00000618601.5
    4. XM_047442033.1XP_047297989.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      Related
      ENSP00000479348.2, ENST00000612846.5
    5. XM_047442037.1XP_047297993.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    6. XM_047442032.1XP_047297988.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
      Related
      ENSP00000479822.2, ENST00000619586.5
    7. XM_047442035.1XP_047297991.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      52231792..52279984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054326919.1XP_054182894.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    2. XM_054326916.1XP_054182891.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    3. XM_054326917.1XP_054182892.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    4. XM_054326915.1XP_054182890.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    5. XM_054326920.1XP_054182895.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    6. XM_054326914.1XP_054182889.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    7. XM_054326918.1XP_054182893.1  protein FAM156A/FAM156B isoform X1

      UniProtKB/Swiss-Prot
      B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
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