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    snrnp35 small nuclear ribonucleoprotein 35 (U11/U12) [ Danio rerio (zebrafish) ]

    Gene ID: 569999, updated on 2-Nov-2024

    Summary

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    Official Symbol
    snrnp35provided by ZNC
    Official Full Name
    small nuclear ribonucleoprotein 35 (U11/U12)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050706-77
    See related
    Ensembl:ENSDARG00000099913 AllianceGenome:ZFIN:ZDB-GENE-050706-77
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112337
    Summary
    Predicted to enable mRNA binding activity and snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex. Orthologous to human SNRNP35 (small nuclear ribonucleoprotein U11/U12 subunit 35). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See snrnp35 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (44373349..44378142)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (44456657..44461450)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene zinc finger, SWIM-type containing 6 Neighboring gene strawberry notch homolog 1 (Drosophila) Neighboring gene lysine methyltransferase 5Aa Neighboring gene CAP-GLY domain containing linker protein 1b Neighboring gene density-regulated protein Neighboring gene CAP-Gly domain-containing linker protein 1 Neighboring gene Rab interacting lysosomal protein-like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112337

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    U11/U12 small nuclear ribonucleoprotein 35 kDa protein
    Names
    U1 snRNP-binding protein homolog
    U11/U12 snRNP 35 kDa protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030241.2 → NP_001025412.1  U11/U12 small nuclear ribonucleoprotein 35 kDa protein

      See identical proteins and their annotated locations for NP_001025412.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01073060
      UniProtKB/Swiss-Prot
      Q4KMD3
      Related
      ENSDARP00000135151.1, ENSDART00000172191.2
      Conserved Domains (2) summary
      COG0724
      Location:47 → 172
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12237
      Location:47 → 139
      RRM_snRNP35; RNA recognition motif found in U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12-35K) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      44373349..44378142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4KMD3.1 GenPept UniProtKB/Swiss-Prot:Q4KMD3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.