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    ess2 ess-2 splicing factor homolog [ Danio rerio (zebrafish) ]

    Gene ID: 324123, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ess2provided by ZNC
    Official Full Name
    ess-2 splicing factor homologprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2843
    See related
    Ensembl:ENSDARG00000060922 AllianceGenome:ZFIN:ZDB-GENE-030131-2843
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dgcr14; fc19d10; wu:fc19d10; zgc:162979
    Summary
    Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human ESS2 (ess-2 splicing factor homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ess2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (42089267..42108146, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (42260887..42279766, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene carbonic anhydrase 15 Neighboring gene DiGeorge syndrome critical region gene 2 Neighboring gene STAM binding protein a Neighboring gene dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative mapping of the 22q11.2 deletion region and the potential of simple model organisms. Guna A, et al. J Neurodev Disord, 2015. PMID 26137170, Free PMC Article
    2. Mitochondrial proteins encoded by the 22q11.2 neurodevelopmental locus regulate neural stem and progenitor cell proliferation. Campbell PD, et al. Mol Psychiatry, 2023 Sep. PMID 37794116, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    splicing factor ESS-2 homolog
    Names
    DiGeorge syndrome critical region gene 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089330.2 → NP_001082799.2  splicing factor ESS-2 homolog

      Status: VALIDATED

      Source sequence(s)
      BX005309, CK016436
      UniProtKB/TrEMBL
      A0A8M1NCU3, F1QAX0
      Related
      ENSDARP00000116212.1, ENSDART00000132976.3
      Conserved Domains (1) summary
      pfam09751
      Location:31 → 396
      Es2; Nuclear protein Es2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      42089267..42108146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394798.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      236689..255568 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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