rpl18 ribosomal protein L18 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rpl18provided by ZNC
Official Full Name: ribosomal protein L18provided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-165
See related: Ensembl:ENSDARG00000029533 AllianceGenome:ZFIN:ZDB-GENE-040801-165
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa98d03; zgc:92872; wu:fa98d03
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within erythrocyte maturation. Predicted to be located in ribosome and rough endoplasmic reticulum. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in eye; head; intestine; liver; and pectoral fin bud. Used to study Diamond-Blackfan anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Orthologous to human RPL18 (ribosomal protein L18). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (16977790..16991808)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (17069813..17083831)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia.
Title: The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia.

Submit: New GeneRIF Correction

General gene information

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Markers

fk41e11.x1 (e-PCR)
- UniSTS:200985

fc20a03.y1 (e-PCR)
- UniSTS:192967

fa93d10.x1 (e-PCR)
- UniSTS:189677

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within erythrocyte maturation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 60S ribosomal protein L18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.