Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Envelope surface glycoprotein gp120
|
env
|
HIV-1 gp120 binds to mannose receptor on vaginal epithelial cells |
PubMed
|
|
env
|
Mannose receptor (MR) dimers bind to soluble monomeric and trimeric HIV envelope and to HIV virion in capture assay |
PubMed
|
|
env
|
Recombinant HIV-1 gp120 blocks Mannose Receptor-mediated phagocytosis in human and murine macrophages and microglial cells |
PubMed
|
|
env
|
HIV-1 gp120 binds to B cells through mannose C-type lectin receptors (MCLRs), such as DC-SIGN, mannose receptor, and langerin |
PubMed
|
|
env
|
HIV-1 gp120 interaction with human mannose receptor (hMR) results in increased production of matrix metalloproteinase-2 (MMP-2) in astrocytes |
PubMed
|
Tat
|
tat
|
HIV-1 Tat represses transcription from the rat mannose receptor promoter, thereby downregulating expression of mannose receptor |
PubMed
|
|
tat
|
HIV-1 Tat interaction with cyclin T1 is required for the repression of mannose receptor (MR) and bone morphogenetic protein receptor-2 (BMPR2) promoters |
PubMed
|
Go to the HIV-1, Human Interaction Database