mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mgat5provided by ZNC
Official Full Name: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060616-238
See related: Ensembl:ENSDARG00000071506 AllianceGenome:ZFIN:ZDB-GENE-060616-238
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mgat5a; zgc:136939; si:dkeyp-4h4.2
Summary: Predicted to enable alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity. Acts upstream of or within neuromast hair cell differentiation involved in neuromast regeneration. Predicted to be located in Golgi membrane and extracellular region. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in gut and nervous system. Orthologous to human MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (11972820..12091448)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (11943138..12061766)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within neuromast hair cell differentiation involved in neuromast regeneration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein N-linked glycosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tissue regeneration	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

Names: mannoside acetylglucosaminyltransferase 5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase

NP_001038776.1

EC 2.4.1.155

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045311.1 → NP_001038776.1 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

See identical proteins and their annotated locations for NP_001038776.1

Status: PROVISIONAL

Source sequence(s)

BC117664

UniProtKB/TrEMBL

A0A8M1NAP4, Q1ECU6

Related

ENSDARP00000096566.4, ENSDART00000105788.5

Conserved Domains (2) summary

pfam15024
Location:173 → 727

Glyco_transf_18; Glycosyltransferase family 18

pfam15027
Location:3 → 139

DUF4525; Domain of unknown function (DUF4525)