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    gps2 G protein pathway suppressor 2 [ Danio rerio (zebrafish) ]

    Gene ID: 393948, updated on 2-Jul-2024

    Summary

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    Official Symbol
    gps2provided by ZNC
    Official Full Name
    G protein pathway suppressor 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1176
    See related
    Ensembl:ENSDARG00000035558 AllianceGenome:ZFIN:ZDB-GENE-040426-1176
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:63588
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Orthologous to human GPS2 (G protein pathway suppressor 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See gps2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (24063009..24074538)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23559212..23570738)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene CTD nuclear envelope phosphatase 1a Neighboring gene GABA(A) receptor-associated protein a Neighboring gene tumor protein p53 Neighboring gene si:ch211-114c12.5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution. Okuda Y, et al. Dev Dyn, 2006 Mar. PMID 16408288
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC63588

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G protein pathway suppressor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431107.1 → NP_001418036.1  G protein pathway suppressor 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL928875

    2. NM_001431108.1 → NP_001418037.1  G protein pathway suppressor 2 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL928875

    3. NM_200973.4 → NP_957267.2  G protein pathway suppressor 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL928875
      Related
      ENSDARP00000051547.4, ENSDART00000051548.6

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      24063009..24074538
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165131.3 → XP_005165188.1  G protein pathway suppressor 2 isoform X2

      UniProtKB/TrEMBL
      B2GP25, F6P8S4, Q7SZ61
      Related
      ENSDARP00000117918.1, ENSDART00000133355.3
      Conserved Domains (1) summary
      pfam15991
      Location:5 → 296
      G_path_suppress; G-protein pathway suppressor

    2. XM_021476040.1 → XP_021331715.1  G protein pathway suppressor 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QDM7
      Conserved Domains (1) summary
      pfam15991
      Location:14 → 304
      G_path_suppress; G-protein pathway suppressor

    3. XM_017356047.2 → XP_017211536.1  G protein pathway suppressor 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QDM7
      Conserved Domains (1) summary
      pfam15991
      Location:14 → 304
      G_path_suppress; G-protein pathway suppressor

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394575.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      69113..80171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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