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    wdr73 WD repeat domain 73 [ Danio rerio (zebrafish) ]

    Gene ID: 550339, updated on 12-Sep-2024

    Summary

    Official Symbol
    wdr73provided by ZNC
    Official Full Name
    WD repeat domain 73provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-126
    See related
    Ensembl:ENSDARG00000023152 AllianceGenome:ZFIN:ZDB-GENE-050417-126
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112071
    Summary
    Acts upstream of or within cerebellar Purkinje cell differentiation and midbrain development. Predicted to be located in cleavage furrow; cytoplasm; and cytoskeleton. Predicted to colocalize with cytosol and spindle pole. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 1. Orthologous to human WDR73 (WD repeat domain 73). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See wdr73 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (21819878..21824285, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (21783242..21787649, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene sialidase 3 (membrane sialidase), tandem duplicate 4 Neighboring gene sialidase 3 (membrane sialidase), tandem duplicate 5 Neighboring gene defensin, beta-like 2 Neighboring gene uncharacterized LOC137488806

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    colocalizes_with spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    WD repeat-containing protein 73

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017646.2NP_001017646.2  WD repeat-containing protein 73

      Status: VALIDATED

      Source sequence(s)
      CU928016
      Related
      ENSDARP00000032408.3, ENSDART00000030984.4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      21819878..21824285 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395090.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      22805..27826 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)