dnaja1 DnaJ heat shock protein family (Hsp40) member A1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dnaja1provided by ZNC
Official Full Name: DnaJ heat shock protein family (Hsp40) member A1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2642
See related: Ensembl:ENSDARG00000030972 AllianceGenome:ZFIN:ZDB-GENE-030131-2642
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dnj-12; dnaja1l; zgc:55650; wu:fc14c09
Summary: Predicted to enable several functions, including ATP binding activity; heat shock protein binding activity; and unfolded protein binding activity. Predicted to act upstream of or within protein folding and response to heat. Predicted to be active in cytosol. Orthologous to human DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (45002998..45014431)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (44301695..44313128)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables Hsp70 protein binding	IEA Inferred from Electronic Annotation more info
enables heat shock protein binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein folding	IEA Inferred from Electronic Annotation more info
involved_in protein refolding	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to heat	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in intracellular membrane-bounded organelle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dnaJ homolog subfamily A member 1

Names: DnaJ (Hsp40) homolog, subfamily A, member 1, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199662.1 → NP_955956.1 dnaJ homolog subfamily A member 1

See identical proteins and their annotated locations for NP_955956.1

Status: PROVISIONAL

Source sequence(s)

BC044445

UniProtKB/TrEMBL

Q803K1

Related

ENSDARP00000011428.5, ENSDART00000021336.7

Conserved Domains (4) summary

cd10719
Location:133 → 199

DnaJ_zf; Zinc finger domain of DnaJ and HSP40

cd10747
Location:104 → 330

DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40

PTZ00037
Location:2 → 395

PTZ00037; DnaJ_C chaperone protein; Provisional

pfam00226
Location:7 → 65

DnaJ; DnaJ domain