papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: papss1provided by ZNC
Official Full Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-080721-5
See related: Ensembl:ENSDARG00000057099 AllianceGenome:ZFIN:ZDB-GENE-080721-5
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sb:eu1009; wu:fc43e12; zgc:194984; zgc:194985
Summary: Predicted to enable adenylylsulfate kinase activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Orthologous to human PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (50487586..50527964, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (49843760..49884138, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc43e12.x1 (e-PCR)
- UniSTS:188168

fj51e02.y1 (e-PCR)
- UniSTS:199497

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables adenylylsulfate kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenylylsulfate kinase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables sulfate adenylyltransferase (ATP) activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sulfate assimilation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sulfate assimilation	IEA Inferred from Electronic Annotation more info
involved_in sulfate assimilation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

NP_001122171.1

EC 2.7.7.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001128699.2 → NP_001122171.1 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

See identical proteins and their annotated locations for NP_001122171.1

Status: VALIDATED

Source sequence(s)

CR788312

UniProtKB/TrEMBL

B3DJF3, B3DJF4, F6NXF1

Related

ENSDARP00000011735.8, ENSDART00000024984.9

Conserved Domains (4) summary

cd00517
Location:254 → 617

ATPS; ATP-sulfurylase

cd02027
Location:54 → 204

APSK; Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of ...

TIGR00339
Location:233 → 616

sopT; ATP sulphurylase

pfam13671
Location:55 → 204

AAA_33; AAA domain