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    ankra2 ankyrin repeat, family A (RFXANK-like), 2 [ Danio rerio (zebrafish) ]

    Gene ID: 406403, updated on 2-Jul-2024

    Summary

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    Official Symbol
    ankra2provided by ZNC
    Official Full Name
    ankyrin repeat, family A (RFXANK-like), 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2141
    See related
    Ensembl:ENSDARG00000035399 AllianceGenome:ZFIN:ZDB-GENE-040426-2141
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:64138; wu:fd08c02
    Summary
    Predicted to be involved in regulation of gene expression. Predicted to be active in nucleus. Orthologous to human ANKRA2 (ankyrin repeat family A member 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ankra2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (34981565..34987273)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (34381412..34387120)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene ectodermal-neural cortex 1 Neighboring gene Rho guanine nucleotide exchange factor (GEF) 28a Neighboring gene forkhead box D1 Neighboring gene basic transcription factor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat family A protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213129.3 → NP_998294.2  ankyrin repeat family A protein 2

      Status: VALIDATED

      Source sequence(s)
      BX530075
      Related
      ENSDARP00000134742.2, ENSDART00000160504.2

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      34981565..34987273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171827.2 → XP_005171884.1  ankyrin repeat family A protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BJM0, A2BGZ3
      Related
      ENSDARP00000123268.1, ENSDART00000134795.3
      Conserved Domains (4) summary
      cd00204
      Location:164 → 288
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:174 → 265
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:141 → 190
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:169 → 200
      ANK; ANK repeat [structural motif]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394590.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      293732..298687
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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