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    TIMM17A translocase of inner mitochondrial membrane 17A [ Homo sapiens (human) ]

    Gene ID: 10440, updated on 2-Nov-2024

    Summary

    Official Symbol
    TIMM17Aprovided by HGNC
    Official Full Name
    translocase of inner mitochondrial membrane 17Aprovided by HGNC
    Primary source
    HGNC:HGNC:17315
    See related
    Ensembl:ENSG00000134375 MIM:605057; AllianceGenome:HGNC:17315
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TIM17; TIM17A
    Summary
    Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial inner membrane and nucleoplasm. Part of TIM23 mitochondrial import inner membrane translocase complex. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal (RPKM 27.6), heart (RPKM 27.5) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See TIMM17A in Genome Data Viewer
    Location:
    1q32.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (201955503..201970664)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (201213194..201228387)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (201924631..201939792)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 2190 Neighboring gene shisa family member 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2324 Neighboring gene leiomodin 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201883337-201883837 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:201910579-201911528 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2325 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:201939921-201940098 Neighboring gene small nucleolar RNA, H/ACA box 70H Neighboring gene ribosomal protein L10 pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by GOA

    General protein information

    Preferred Names
    mitochondrial import inner membrane translocase subunit Tim17-A
    Names
    inner membrane preprotein translocase Tim17a
    mitochondrial inner membrane translocase
    preprotein translocase
    translocase of inner mitochondrial membrane 17 homolog A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_006335.3NP_006326.1  mitochondrial import inner membrane translocase subunit Tim17-A

      See identical proteins and their annotated locations for NP_006326.1

      Status: VALIDATED

      Source sequence(s)
      AC099676, AF106622, AU123184, BC020833
      Consensus CDS
      CCDS1417.1
      UniProtKB/Swiss-Prot
      B2RDM5, Q99595, Q9BWF5
      UniProtKB/TrEMBL
      Q7RU05
      Related
      ENSP00000356256.4, ENST00000367287.5
      Conserved Domains (1) summary
      TIGR00980
      Location:1171
      3a0801so1tim17; mitochondrial import inner membrane translocase subunit tim17

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      201955503..201970664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      201213194..201228387
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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