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    nbr1b NBR1 autophagy cargo receptor b [ Danio rerio (zebrafish) ]

    Gene ID: 555713, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nbr1bprovided by ZNC
    Official Full Name
    NBR1 autophagy cargo receptor bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-170215-1
    See related
    Ensembl:ENSDARG00000078772 AllianceGenome:ZFIN:ZDB-GENE-170215-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Orthologous to human NBR1 (NBR1 autophagy cargo receptor). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See nbr1b in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (32933721..32952043)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (32801978..32820329)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene glucose-6-phosphatase catalytic subunit 1b Neighboring gene amine oxidase copper containing 2 Neighboring gene caspase 6b.1, apoptosis-related cysteine peptidase Neighboring gene caspase 6, apoptosis-related cysteine peptidase a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and characterization of a zebrafish gain-of-function ACOX1 Mitchell disease model. Raas Q, et al. Front Pediatr, 2024. PMID 38357503, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    next to BRCA1 gene 1 protein
    Names
    neighbor of BRCA1 gene 1
    neighbor of brca1 gene 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386643.1 → NP_001373572.1  next to BRCA1 gene 1 protein

      Status: VALIDATED

      Source sequence(s)
      CT583642
      UniProtKB/TrEMBL
      A0A8M1QKU5, F1R2I7
      Related
      ENSDARP00000104318.2, ENSDART00000112742.3
      Conserved Domains (4) summary
      cd06396
      Location:5 → 85
      PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
      cd14319
      Location:944 → 980
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      cd14947
      Location:363 → 470
      NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
      cl00295
      Location:223 → 261
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      32933721..32952043
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021474335.2 → XP_021330010.1  next to BRCA1 gene 1 protein isoform X1

      UniProtKB/TrEMBL
      A0A8M1QKU5, A0A8M9Q9K6
      Conserved Domains (3) summary
      cd06396
      Location:5 → 85
      PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
      cd14319
      Location:930 → 966
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      cd14947
      Location:349 → 456
      NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395227.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      277510..297095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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