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    atrxl ATRX chromatin remodeler, like [ Danio rerio (zebrafish) ]

    Gene ID: 568580, updated on 2-Nov-2024

    Summary

    Official Symbol
    atrxlprovided by ZNC
    Official Full Name
    ATRX chromatin remodeler, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2019
    See related
    Ensembl:ENSDARG00000099449 AllianceGenome:ZFIN:ZDB-GENE-030131-2019
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb94e07
    Summary
    Predicted to enable chromatin DNA binding activity and methylated histone binding activity. Predicted to be involved in chromatin remodeling and replication fork processing. Predicted to be located in pericentric heterochromatin. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in X-linked mental retardation-hypotonic facies syndrome-1; alpha thalassemia-X-linked intellectual disability syndrome; alpha-thalassemia myelodysplasia syndrome; high grade glioma; and lung small cell carcinoma. Orthologous to human ATRX (ATRX chromatin remodeler). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See atrxl in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (23044946..23083932)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene charged multivesicular body protein 1B Neighboring gene cyclic nucleotide gated channel subunit alpha 2b Neighboring gene zinc finger DHHC-type palmitoyltransferase 15a Neighboring gene uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) Neighboring gene neurite extension and migration factor a

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in replication fork processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in pericentric heterochromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ATRX chromatin remodeler, like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001423350.1NP_001410279.1  ATRX chromatin remodeler, like

      Status: VALIDATED

      Source sequence(s)
      CR762398

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      23044946..23083932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221280.1XP_068077381.1  ATRX chromatin remodeler, like isoform X2

    2. XM_068221279.1XP_068077380.1  ATRX chromatin remodeler, like isoform X1

      Related
      ENSDARP00000137092.1, ENSDART00000171719.2

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394574.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      261439..300435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)