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    pdia7 protein disulfide isomerase family A, member 7 [ Danio rerio (zebrafish) ]

    Gene ID: 405841, updated on 27-Mar-2024

    Summary

    Official Symbol
    pdia7provided by ZNC
    Official Full Name
    protein disulfide isomerase family A, member 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2238
    See related
    Ensembl:ENSDARG00000014015 AllianceGenome:ZFIN:ZDB-GENE-040426-2238
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    erp57l1; zgc:77086
    Summary
    Predicted to enable protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in cell surface and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See pdia7 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (30422485..30434260, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (30464558..30476333, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 79b Neighboring gene chaperonin containing TCP1, subunit 3 (gamma) Neighboring gene platelet endothelial aggregation receptor 1 Neighboring gene lamin A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC77086

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein disulfide isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein disulfide isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to endoplasmic reticulum stress IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein disulfide isomerase family A, member 7
    NP_998070.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212905.1NP_998070.1  protein disulfide isomerase family A, member 7 precursor

      See identical proteins and their annotated locations for NP_998070.1

      Status: PROVISIONAL

      Source sequence(s)
      BC067155
      UniProtKB/TrEMBL
      Q6NXB9
      Related
      ENSDARP00000023877.7, ENSDART00000018504.8
      Conserved Domains (5) summary
      cd02995
      Location:368471
      PDI_a_PDI_a'_C; PDIa family, C-terminal TRX domain (a') subfamily; composed of the C-terminal redox active a' domains of PDI, ERp72, ERp57 (or ERp60) and EFP1. PDI, ERp72 and ERp57 are endoplasmic reticulum (ER)-resident eukaryotic proteins involved in oxidative protein ...
      cd03069
      Location:127231
      PDI_b_ERp57; PDIb family, ERp57 subfamily, first redox inactive TRX-like domain b; ERp57 (or ERp60) exhibits both disulfide oxidase and reductase functions like PDI, by catalyzing the formation of disulfide bonds of newly synthesized polypeptides in the ER and acting ...
      cd03073
      Location:235348
      PDI_b'_ERp72_ERp57; PDIb' family, ERp72 and ERp57 subfamily, second redox inactive TRX-like domain b'; ERp72 and ER57 are involved in oxidative protein folding in the ER, like PDI. They exhibit both disulfide oxidase and reductase functions, by catalyzing the formation of ...
      TIGR01130
      Location:20483
      ER_PDI_fam; protein disulfide isomerase, eukaryotic
      cl00388
      Location:25124
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      30422485..30434260 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)