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    dop1a DOP1 leucine zipper like protein A [ Danio rerio (zebrafish) ]

    Gene ID: 448893, updated on 2-Nov-2024

    Summary

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    Official Symbol
    dop1aprovided by ZNC
    Official Full Name
    DOP1 leucine zipper like protein Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050309-65
    See related
    Ensembl:ENSDARG00000019962 AllianceGenome:ZFIN:ZDB-GENE-050309-65
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dopey1; im:6911215; im:7148241
    Summary
    Predicted to act upstream of or within Golgi to endosome transport. Predicted to be active in endosome and trans-Golgi network. Orthologous to human DOP1A (DOP1 leucine zipper like protein A). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dop1a in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (33062327..33097384, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (33108516..33143362, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 91a Neighboring gene clathrin coat assembly protein AP180-like Neighboring gene proline-rich nuclear receptor coactivator 2 Neighboring gene cannabinoid receptor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation. Gallagher TL, et al. Dev Biol, 2017 Sep 1. PMID 28648842, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi to endosome transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein dopey-1
    Names
    dopey family member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      33062327..33097384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009292499.4 → XP_009290774.1  protein dopey-1 isoform X1

      See identical proteins and their annotated locations for XP_009290774.1

      UniProtKB/TrEMBL
      A0A8M3AQT1, F1R226
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 297
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2104 → 2423
      Dopey_N; Dopey, N-terminal

    2. XM_009292500.4 → XP_009290775.1  protein dopey-1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PUY5
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 295
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2095 → 2414
      Dopey_N; Dopey, N-terminal

    3. XM_009292501.4 → XP_009290776.1  protein dopey-1 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AJB2
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 297
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2094 → 2413
      Dopey_N; Dopey, N-terminal

    4. XM_009292498.4 → XP_009290773.1  protein dopey-1 isoform X1

      See identical proteins and their annotated locations for XP_009290773.1

      UniProtKB/TrEMBL
      A0A8M3AQT1, F1R226
      Related
      ENSDARP00000133813.1, ENSDART00000166617.2
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 297
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2104 → 2423
      Dopey_N; Dopey, N-terminal

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394965.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      79682..114739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473017.2 → XP_021328692.1  protein dopey-1 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AQT1, F1R226
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 297
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2104 → 2423
      Dopey_N; Dopey, N-terminal

    2. XM_021473019.2 → XP_021328694.1  protein dopey-1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PUY5
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 295
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2095 → 2414
      Dopey_N; Dopey, N-terminal

    3. XM_021473020.2 → XP_021328695.1  protein dopey-1 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AJB2
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 297
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2094 → 2413
      Dopey_N; Dopey, N-terminal

    4. XM_021473018.2 → XP_021328693.1  protein dopey-1 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AQT1, F1R226
      Conserved Domains (2) summary
      pfam04118
      Location:13 → 297
      Dopey_N; Dopey, N-terminal
      cl04407
      Location:2104 → 2423
      Dopey_N; Dopey, N-terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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