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    inpp5l inositol polyphosphate-5-phosphatase L [ Danio rerio (zebrafish) ]

    Gene ID: 641571, updated on 12-Sep-2024

    Summary

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    Official Symbol
    inpp5lprovided by ZNC
    Official Full Name
    inositol polyphosphate-5-phosphatase Lprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051127-29
    See related
    Ensembl:ENSDARG00000053878 AllianceGenome:ZFIN:ZDB-GENE-051127-29
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:123248
    Summary
    Predicted to enable inositol-polyphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate dephosphorylation and inositol phosphate-mediated signaling. Predicted to act upstream of or within phosphatidylinositol dephosphorylation. Orthologous to human INPP5A (inositol polyphosphate-5-phosphatase A). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See inpp5l in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (38421333..38477819, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (38390409..38444849, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase NEURL3 Neighboring gene NK6 homeobox 3 Neighboring gene C2 calcium-dependent domain-containing protein 4C Neighboring gene forkhead box B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Effects of miR-181a-5p abnormal expression on zebrafish (Danio rerio) vascular development following triclosan exposure. Ma Y, et al. Chemosphere, 2019 May. PMID 30784759
    2. Modulation of dorsal root ganglion development by ErbB signaling and the scaffold protein Sorbs3. Malmquist SJ, et al. Development, 2013 Oct. PMID 24004948, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123248

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-polyphosphate 5-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables inositol-polyphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inositol polyphosphate-5-phosphatase A
    NP_001032658.2
    XP_068079121.1
    XP_068079122.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037569.2 → NP_001032658.2  inositol polyphosphate-5-phosphatase A

      Status: VALIDATED

      Source sequence(s)
      BX571947
      UniProtKB/TrEMBL
      Q2YDR0
      Related
      ENSDARP00000070468.5, ENSDART00000075989.6

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      38421333..38477819 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223020.1 → XP_068079121.1  inositol polyphosphate-5-phosphatase A isoform X1

    2. XM_068223021.1 → XP_068079122.1  inositol polyphosphate-5-phosphatase A isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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